ELISA/assay

Human PEDF/SerpinF1 ELISA Kit PicoKine®

EK0896

1

Human PEDF/SerpinF1 ELISA Kit PicoKine®

human-pedf-serpinf1-picokine-trade-elisa-kit-ek0896-boster

Picokine ELISA Kits

SERPINF1

369

156 pg/ml - 10,000 pg/ml

Human PEDF/SerpinF1 ELISA Kit PicoKine (96 Tests). Quantitate Human SERPINF1 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 20pg/ml.

Human PEDF/SerpinF1 ELISA Kit PicoKine (96 Tests). Quantitate Human SERPINF1 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 20pg/ml.

96 wells/kit, with removable strips.

P36955

Expression system for standard: NS0; Immunogen sequence: M1-P418

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

There is no detectable cross-reactivity with other relevant proteins.

<20 pg/ml

50 ng/tube

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).

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人类

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Human PEDF/SerpinF1 PicoKine ELISA Kit standard curve

Concentration (pg/ml) 0 156 312 625 1250 2500 5000 10000 O.D. 0.006 0.011 0.240 0.408 0.659 1.021 1.410 1.956

9/16/15 20:50

3/2/22 2:55

Human PEDF/SerpinF1 ELISA Kit Price PicoKine® BosterBio

Human PEDF/SerpinF1 ELISA Kit, Bosterbio High Sensitivity

97

肝素或乙二胺四乙酸

10,000 pg/ml, 5,000 pg/ml, 2,500 pg/ml, 1,250 pg/ml, 625 pg/ml, 312 pg/ml, 156 pg/ml

Pigment epithelium-derived factor (PEDF) is also known as serpin F1 (SERPINF1). In humans, it is encoded by the SERPINF1 gene. PEDF has a variety of functions including antiangiogenic, antitumorigenic, and neurotrophic properties. It suppresses retinal neovascularization and endothelial cell proliferation. And Antiangiogenic function is also conferred by PEDF through inhibition of both VEGFR-1 and VEGFR-2. In addition, the antitumorigenic effects of PEDF are not only due to inhibition of supporting vasculature, but also due to effects on the cancer cells themselves. PEDF is shown to inhibit cancer cell proliferation and increase apoptosis via the FAS/FASL pathway. Expression of PEDF in the human retina is found at 7.4 weeks of gestation, suggesting it may play a role in retinal neuron differentiation.

Angiogenesis,Cancer,Cardiovascular,Invasion/Microenvironment,Neurogenesis,Neurology Process,Neuroscience,Sensory System,Visual System

Pigment epithelium-derived factor;PEDF;Cell proliferation-inducing gene 35 protein;EPC-1;Serpin F1;SERPINF1;PEDF;PIG35;

Pigment epithelium-derived factor

46312分子量

Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

Secreted . Melanosome . Enriched in stage I melanosomes.

视网膜色素上皮细胞 和血血浆

Pigment epithelium-derived factor

Intra-Assay Precision Inter-Assay Precision Sample 1 2 3 1 2 3 n 16 16 16 24 24 24 Mean (pg/ml) 286 780 2612 271 802 2714 Standard deviation 19.16 44.46 104 48 19.51 53.73 130.27 CV (%) 6.7% 5.7% 4% 7.2% 6.7% 4.8%

Lots Lot 1 (pg/ml) Lot 2 (pg/ml) Lot 3 (pg/ml) Lot 4 (pg/ml) Mean (pg/ml) Standard Deviation CV (%) Sample 1 286 285 271 293 284 13.05 4.6% Sample 2 780 796 821 805 801 33.62 4.2% Sample 3 2612 2744 2752 2653 2690 104.92 3.9% *number of samples for each test n=16.

15-25min

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