产品简要
信息索取 :
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
ELISA/assay
产品名称 :
Human PLAT/TPA PicoKine ELISA Kit
目录 :
EK0897
规格 :
96 wells/kit
价格 :
399美元
产品信息
SKU号 :
EK0897
名称 :
Human PLAT/TPA PicoKine ELISA Kit
价格 :
399美元
免疫原 :
Expression system for standard: CHO; Immunogen sequence: M1-P562
描述 :
Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human PLAT/TPA
规格 :
96 wells/kit
反应物种 :
人类
应用 :
酶联免疫吸附测定
背景 :
Plasminogen activator, tissue, also called PLAT or TPA is a serine protease. This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This gene was mapped to 8p11.21. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism.
交叉活性 :
There is no detectable cross-reactivity with other relevant proteins.
基因全称 :
组织类型纤溶酶原激活剂
基因名称 :
PLAT
protein function :
Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. Plays a direct role in facilitating neuronal migration.
蛋白名 :
组织类型纤溶酶原激活剂
研究种类 :
Nothing Found
sequence similarities :
Belongs to the peptidase S1 family.
储存 :
Store at 4ËšC for 6 months, at -20ËšC for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
subcellular localization :
Secreted, extracellular space.
同义词 :
Tissue-type plasminogen activator;t-PA;t-plasminogen activator;tPA;3.4.21.68;Alteplase;Reteplase;Tissue-type plasminogen activator chain A;Tissue-type plasminogen activator chain B;PLAT;
组织特异性 :
Synthesized in numerous tissues (including tumors) and secreted into most extracellular body fluids, such as plasma, uterine fluid, saliva, gingival crevicular fluid, tears, seminal fluid, and milk.
UniProt数据库编号 :
P00750
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
www.boster.com.cn
925.485.4527
公司总部: 美国
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