产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
ELISA/assay
产品名称 :
Human KLK1/Kallikrein 1 ELISA Kit PicoKine®
目录 :
EK0903
规格 :
96 wells/kit, with removable strips.
价格 :
420美元
文章摘录数: 1
参考文献
Scarisbrick I, Linbo R, Vandell A, Keegan M, Blaber S, Blaber M, et al. Kallikreins are associated with secondary progressive multiple sclerosis and promote neurodegeneration. Biol Chem. 2008;389:739-45 pubmed 出版商
图像
图像 1 :
武汉博士德生物工程有限公司 EK0903 图像 1
Human KLK1 PicoKine ELISA Kit standard curve
产品信息
SKU号 :
EK0903
产品名称 :
Human KLK1/Kallikrein 1 ELISA Kit PicoKine®
规格 :
96 wells/kit, with removable strips.
价格 :
420美元
描述 :
Human KLK1/Kallikrein 1 ELISA Kit PicoKine® (96 Tests). Quantitate Human KLK1 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.
反应物种 :
人类
应用 :
酶联免疫吸附测定
基因名称 :
KLK1
UniProt数据库编号 :
P06870
免疫原 :
Expression system for standard: NS0; Immunogen sequence: I25-S262
交叉活性 :
There is no detectable cross-reactivity with other relevant proteins.
试验范围 :
156 pg/ml - 10,000 pg/ml
敏感性 :
<10 pg/ml
样品类型 :
cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)
Capture/Detection Antibodies :
单克隆抗体来自小鼠, 多克隆抗体来自山羊
储存 :
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
基因全称 :
激肽释放酶1
同义词 :
激肽释放酶1;3.4。 21.35;肾脏/胰腺/唾腺激肽释放酶;组织激肽释放酶;KLK1;
蛋白名 :
激肽释放酶1
分子量 :
28890分子量
Protein Function :
Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
组织特异性 :
Isoform 2 is expressed in pancreas, salivary glands, kidney, colon, prostate gland, testis, spleen and the colon adenocarcinoma cell line T84.
Sequence Similarities :
Belongs to the peptidase S1 family. Kallikrein subfamily.
背景 :
Kallikrein-1, also known as tissue kallikrein, is a protein that in humans is encoded by the KLK1 gene. This serine protease generates Lys-bradykinin by specific proteolysis of kininogen-1. KLK1 is a member of the peptidase S1 family. Its gene is mapped to 19q13.3. In all, it has got 262-amino acids which contain a putative signal peptide, followed by a short activating peptide and the protease domain. The protein is mainly found in kidney, pancreas, and salivary gland, showing a unique pattern of tissue-specific expression relative to other members of the family. KLK1 is implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers.
研究种类 :
Angiogenesis, Cancer, Cardiovascular, Cell Biology, Cytoskeleton / Ecm, Ecm Enzymes, Extracellular Matrix, Invasion/Microenvironment, Proteolysis / Ubiquitin, Proteolytic Enzymes, Serum Proteins, Signal Transduction
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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