ELISA/assay

Human Aggrecan/ACAN ELISA Kit PicoKine®

EK0909

96 wells/kit, with removable strips.

369美元

Human Aggrecan/ACAN ELISA Kit PicoKine®

96 wells/kit, with removable strips.

369美元

Human Aggrecan ELISA Kit PicoKine® (96 Tests). Quantitate Human ACAN in cell culture supernatants, serum and urine. Sensitivity: 50pg/ml.

人类

酶联免疫吸附测定

ACAN

P16112

Expression system for standard: NS0; Immunogen sequence: V20-R675

There is no detectable cross-reactivity with other relevant proteins.

1.56 ng/ml - 100 ng/ml

<50 pg/ml

cell culture supernatants, serum and urine

多克隆抗体来自山羊, 多克隆抗体来自山羊

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Aggrecan core protein

Aggrecan core protein;Cartilage-specific proteoglycan core protein;CSPCP;Chondroitin sulfate proteoglycan core protein 1;Chondroitin sulfate proteoglycan 1;Aggrecan core protein 2;ACAN;AGC1, CSPG1, MSK16;

Aggrecan core protein

250193分子量

This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region.

Secreted, extracellular space, extracellular matrix .

Restricted to cartilages.

Aggrecan, also known as cartilage-specific proteoglycan core protein (CSPCP) or chondroitin sulfate proteoglycan 1, is a protein that in humans is encoded by the ACAN gene. It is a critical component for cartilage structure and the function of joints. Aggrecan provides intervertebral disc and cartilage with the ability to resist compressive loads. The localized high concentrations of aggrecan provide the osmotic properties necessary for normal tissue function with the GAGs producing the swelling pressure that counters compressive loads on the tissue. This functional ability is dependent on a high GAG/aggrecan concentration being present in the tissue extracellular matrix. Also, Aggrecan plays an important role in the organization of the extracellular spaces between neurons in the brain.

Cytoskeleton / Ecm, Ecm Proteins, Extracellular Matrix, Mesenchymal Stem Cells, Signal Transduction, Stem Cells