产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
ELISA/assay
产品名称 :
Bovine Endothelin 1/EDN1 ELISA Kit PicoKine®
目录 :
EK0945-BV
规格 :
96 wells/kit, with removable strips.
价格 :
369美元
文章摘录数: 3
参考文献
Jankowska Lech I, Terelak Borys B, Grabska Liberek I, Palasik W, Bik W, WoliÅ„ska Witort E. Decreased endothelin-1 plasma levels in multiple sclerosis patients: a possible factor of vascular dysregulation?. Med Sci Monit. 2015;21:1066-71 pubmed 出版商
Groesdonk H, Raffel M, Speer T, Bomberg H, Schmied W, Klingele M, et al. Elevated endothelin-1 level is a risk factor for nonocclusive mesenteric ischemia. J Thorac Cardiovasc Surg. 2015;149:1436-42.e2 pubmed 出版商
Wang G, Hu S, Sun J. [Effects of carvedilol on circulating levels of endothelin and von Willebrand factor in patients with unstable angina pectoris]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2002;31:340-343 pubmed
图像
图像 1 :
武汉博士德生物工程有限公司 EK0945-BV 图像 1
Bovine Endothelin PicoKine ELISA Kit standard curve
产品信息
SKU号 :
EK0945-BV
产品名称 :
Bovine Endothelin 1/EDN1 ELISA Kit PicoKine®
规格 :
96 wells/kit, with removable strips.
价格 :
369美元
描述 :
Bovine Endothelin 1/EDN1 ELISA Kit PicoKine® (96 Tests). Quantitate Bovine EDN1 in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 0.5pg/ml.
反应物种 :
应用 :
酶联免疫吸附测定
基因名称 :
EDN1
UniProt数据库编号 :
P17322
免疫原 :
Expression system for standard: bovine peptide; Immunogen sequence: C53-W73
交叉活性 :
There is no detectable cross-reactivity with other relevant proteins.
试验范围 :
3.9 pg/ml - 250 pg/ml
敏感性 :
<0.5 pg/ml
样品类型 :
cell culture supernatants, serum and plasma (heparin, EDTA)
Capture/Detection Antibodies :
单克隆抗体来自小鼠, 多克隆抗体来自山羊
储存 :
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
基因全称 :
内皮素1
同义词 :
内皮素1;前内皮素原1;PPET1;内皮素1;ET-1;大内皮素1;EDN1;
蛋白名 :
内皮素1
分子量 :
24425分子量
Protein Function :
Endothelins are endothelium-derived vasoconstrictor peptides.
Subcellular Localization :
Secreted.
组织特异性 :
Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.
Sequence Similarities :
Belongs to the endothelin/sarafotoxin family.
背景 :
The endothelins is a family of structurally and pharmacologically distinct peptides, which has been identified and sequenced in humans. Three isoforms of Bovine endothelin have been identified: endothelin-1, -2, and -3. Endothelin-1 is a potent, 21-amino acid vasoconstrictor peptide produced by vascular endothelial cells. Endothelins are 21-amino acid vasoconstricting peptides produced primarily in the endothelium having a key role in vascular homeostasis. Endothelins are implicated in vascular diseases of several organ systems, including the heart, general circulation and brain. Endothelins are proteins that constrict blood vessels and raise blood pressure. They are normally kept in balance by other mechanisms, but when they are over-expressed, they contribute to high blood pressure (hypertension) and heart disease.
研究种类 :
Cancer, Cancer Metabolism, Cardiovascular, Growth Factors/Hormones, Metabolism, Metabolism Processes, Pathways And Processes, Response To Hypoxia, Signal Transduction, Vasculature
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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