产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
ELISA/assay
产品名称 :
Mouse Complement C5a ELISA Kit PicoKine®
目录 :
EK0987
规格 :
96 wells/kit, with removable strips.
价格 :
369美元
文章摘录数: 1
参考文献
Munenaga S, Ouhara K, Hamamoto Y, Kajiya M, Takeda K, Yamasaki S, et al. The involvement of C5a in the progression of experimental arthritis with Porphyromonas gingivalis infection in SKG mice. Arthritis Res Ther. 2018;20:247 pubmed 出版商
图像
图像 1 :
武汉博士德生物工程有限公司 EK0987 图像 1
Mouse Complement C5a PicoKine ELISA Kit standard curve
产品信息
SKU号 :
EK0987
产品名称 :
Mouse Complement C5a ELISA Kit PicoKine®
规格 :
96 wells/kit, with removable strips.
价格 :
369美元
描述 :
Mouse Complement C5a ELISA Kit PicoKine® (96 Tests). Quantitate Mouse C5 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.
反应物种 :
小鼠
应用 :
酶联免疫吸附测定
基因名称 :
C5
UniProt数据库编号 :
P06684
免疫原 :
Expression system for standard: E.coli; Immunogen sequence: N679-R755
交叉活性 :
There is no detectable cross-reactivity with other relevant proteins.
试验范围 :
15.6 pg/ml - 1,000 pg/ml
敏感性 :
<10 pg/ml
样品类型 :
cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)
Capture/Detection Antibodies :
单克隆抗体来自大鼠, 多克隆抗体来自山羊
储存 :
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
基因全称 :
补体C5
同义词 :
Complement C5;Hemolytic complement;Complement C5 beta chain;Complement C5 alpha chain;C5a anaphylatoxin;Complement C5 alpha' chain;C5;Hc;
蛋白名 :
补体C5
分子量 :
188878分子量
Protein Function :
Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled.
Subcellular Localization :
Secreted.
Sequence Similarities :
Contains 1 anaphylatoxin-like domain.
背景 :
C5a is a protein fragment released from complement component C5. This gene is mapped to 9q33.2. The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to susceptibility to liver fibrosis and to rheumatoid arthritis.
研究种类 :
ChIP’ing Antibodies, Domain Families, Epigenetics and Nuclear Signaling, Hlh / Leucine Zipper, Immunology, Innate Immunity, Transcription
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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