ELISA/assay

Mouse CCL12/MCP5 ELISA Kit PicoKine®

EK1128

96 wells/kit, with removable strips.

369美元

Mouse CCL12/MCP5 ELISA Kit PicoKine®

96 wells/kit, with removable strips.

369美元

Mouse CCL12/MCP5 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Ccl12 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

小鼠

酶联免疫吸附测定

Ccl12

Q62401

Expression system for standard: E.coli; Immunogen sequence: G23-G104

There is no detectable cross-reactivity with other relevant proteins.

31.2 pg/ml - 2,000 pg/ml

<10 pg/ml

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

单克隆抗体来自大鼠, 多克隆抗体来自山羊

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

C-C motif chemokine 12

C-C motif chemokine 12;MCP-1-related chemokine;Monocyte chemoattractant protein 5;Monocyte chemotactic protein 5;MCP-5;Small-inducible cytokine A12;Ccl12;Mcp5, Scya12;

C-C motif chemokine 12

11659分子量

Chemotactic factor that attracts eosinophils, monocytes, and lymphocytes but not neutrophils. Potent monocyte active chemokine that signals through CCR2. Involved in allergic inflammation and the host response to pathogens and may play a pivotal role during early stages of allergic lung inflammation.

Secreted.

Predominantly expressed in the lymph nodes and thymus. Also found in the salivary glands containing lymph nodes, breast, heart, lung, brain, small intestine, kidney and colon.

Chemokine (C-C motif) ligand 12 (CCL12) is a small cytokine belonging to the CC chemokine family that has been described in mice. It is also known as monocyte chemotactic protein 5 (MCP-5) and, due to its similarity with the human chemokine MCP-1, sometimes it is called MCP-1-related chemokine. CCL12 specifically attracts eosinophils, monocytes and lymphocytes. This chemokine is found predominately in lymph nodes and thymus under normal conditions, and its expression can be hugely induced in macrophages. It is thought to coordinate cell movements during early allergic reactions, and immune response to pathogens. The gene for CCL12 is found in a cluster of CC chemokines on mouse chromosome 11.

Chemokines, Immunology, Innate Immunity