产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
ELISA/assay
产品名称 :
Mouse CD163 ELISA Kit PicoKine®
目录 :
EK1146
规格 :
96 wells/kit, with removable strips.
价格 :
369美元
图像
图像 1 :
武汉博士德生物工程有限公司 EK1146 图像 1
Mouse CD163 PicoKine ELISA Kit standard curve
产品信息
SKU号 :
EK1146
产品名称 :
Mouse CD163 ELISA Kit PicoKine®
规格 :
96 wells/kit, with removable strips.
价格 :
369美元
描述 :
Mouse CD163 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Cd163 in cell culture supernatants, serum and plasma (heparin). Sensitivity: 20pg/ml.
反应物种 :
小鼠
应用 :
酶联免疫吸附测定
基因名称 :
CD163
UniProt数据库编号 :
Q2VLH6
免疫原 :
Expression system for standard: NS0; Immunogen sequence: V39-T1045
交叉活性 :
There is no detectable cross-reactivity with other relevant proteins.
试验范围 :
0.78 ng/ml - 50 ng/ml
敏感性 :
<20 pg/ml
样品类型 :
cell culture supernatants, serum and plasma (heparin)
Capture/Detection Antibodies :
单克隆抗体来自大鼠, 多克隆抗体来自山羊
储存 :
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
基因全称 :
Scavenger receptor cysteine-rich type 1 protein M130
同义词 :
Scavenger receptor cysteine-rich type 1 protein M130;CD163;Soluble CD163;sCD163;Cd163;M130;
蛋白名 :
Scavenger receptor cysteine-rich type 1 protein M130
分子量 :
120921分子量
Protein Function :
Involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium- dependent and pH-dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1 (By similarity).
Subcellular Localization :
Soluble CD163: Secreted .
组织特异性 :
Expressed in monocytes and mature macrophages such as Kupffer cells in the liver, red pulp macrophages in the spleen and mesenteric lymph nodes.
背景 :
CD163 (Cluster of Differentiation 163) is a human protein encoded by the CD163 gene. It has also been shown to mark cells of monocyte/macrophage lineage. CD163, a member of the scavenger receptor cysteine-rich (SRCR) superfamily, is exclusively expressed by monocytes and macrophages. Using FISH, somatic cell hybrid analysis, and radiation hybrid analysis, CD163 gene was mapped the to chromosome 12p13.3. CD163 is upregulated in a large range of diseases inflammatory diseases including type 2 diabetes, macrophage activation sickness, Tangier's disease, reumatoid arthritis etc.
研究种类 :
Atherosclerosis, Cardiovascular, Cell Type Markers, Immunology, Innate Immunity, Macrophage / Inflamm., Vascular Inflammation
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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