产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
ELISA/assay
产品名称 :
Human AGT/Serpin A8/Angiotensinogen ELISA Kit PicoKine®
目录 :
EK1465
规格 :
96 wells/kit, with removable strips.
价格 :
399美元
图像
图像 1 :
武汉博士德生物工程有限公司 EK1465 图像 1
Human AGT PicoKine ELISA Kit standard curve
产品信息
SKU号 :
EK1465
产品名称 :
Human AGT/Serpin A8/Angiotensinogen ELISA Kit PicoKine®
规格 :
96 wells/kit, with removable strips.
价格 :
399美元
描述 :
Human AGT/Serpin A8/Angiotensinogen ELISA Kit PicoKine® (96 Tests). Quantitate Human AGT in cell culture supernatants, serum and plasma (EDTA). Sensitivity: 10pg/ml.
反应物种 :
人类
应用 :
酶联免疫吸附测定
基因名称 :
AGT
UniProt数据库编号 :
P01019
免疫原 :
Expression system for standard: NS0; Immunogen sequence: D34-A485
交叉活性 :
There is no detectable cross-reactivity with other relevant proteins.
试验范围 :
312 pg/ml - 20,000 pg/ml
敏感性 :
<10 pg/ml
样品类型 :
cell culture supernatants, serum and plasma (EDTA)
Capture/Detection Antibodies :
a单克隆抗体来自小鼠, a生物素多克隆抗体来自山羊
储存 :
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
基因全称 :
血管紧张素
同义词 :
Angiotensinogen; Serpin A8; Angiotensin-1; Angiotensin 1-10; Angiotensin I; Ang I; Angiotensin-2; Angiotensin 1-8; Angiotensin II; Ang II; Angiotensin-3; Angiotensin 2-8; Angiotensin III; Ang III; Des-Asp[1]-angiotensin II; Angiotensin-4; Angiotensin 3-8; Angiotensin IV; Ang IV; Angiotensin 1-9; Angiotensin 1-7; Angiotensin 1-5; Angiotensin 1-4; AGT; SERPINA8
Protein Function :
Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis.
Subcellular Localization :
Secreted.
组织特异性 :
Expressed by the liver and secreted in plasma.
背景 :
AGT (ANGIOTENSINOGEN), also called SERPINA8, is an α-2-globulin that is produced constitutively and released into the circulation mainly by the liver. ATG is a member of the serpin family, although it is not known to inhibit other enzymes, unlike most serpins. Angiotensinogen is also known as renin substrate. The AGT gene is mapped on 1q42.2. And the human angiotensinogen gene contains 5 exons. The expression of AGT and enzymes required for its conversion to angiotensin II in human adipose tissue. Mutations in this AGT gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
研究种类 :
Cardiovascular, G Protein Signaling, Signal Transduction, Signaling Pathway
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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