ELISA/assay

Mouse TNFRSF19/TROY ELISA Kit PicoKine®

EK1585

96 wells/kit, with removable strips.

369美元

Mouse TNFRSF19/TROY ELISA Kit PicoKine®

96 wells/kit, with removable strips.

369美元

Mouse TNFRSF19/TROY ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Tnfrsf19 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 12pg/ml.

小鼠

酶联免疫吸附测定

Tnfrsf19

Q9JLL3

Expression system for standard: NS0; Immunogen sequence: E30-L170

There is no detectable cross-reactivity with other relevant proteins.

62.5 pg/ml - 4,000 pg/ml

<12 pg/ml

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

单克隆抗体来自大鼠, 多克隆抗体来自山羊

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Tumor necrosis factor receptor superfamily member 19

Tumor necrosis factor receptor superfamily member 19;TRADE;Toxicity and JNK inducer;Tnfrsf19;Taj, Troy;

Tumor necrosis factor receptor superfamily member 19

45265分子量

Can mediate activation of c-Jun and NF-kappa-B. May promote caspase-independent cell death (By similarity). Isoform 2 and isoform 3 may act as decoy receptors.

Isoform 1: Cell membrane ; Single-pass type I membrane protein .

Highly expressed in adult brain, and in embryos from day 11-17, but not earlier. Detected in embryonic brain and epithelium, and at lower levels in adult heart, lung and liver. In neonatal mice, mainly in hair follicles and neuron-like cells in the cerebellum, but not in the skin epidermis. Isoform 3 was found in embryonic day 17.5 skin but not in brain and liver.

Tumor necrosis factor receptor superfamily, member 19, also known as TNFRSF19 and TROY, is a human gene. It is mapped to 13q12.11-q12.3. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. This receptor is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Apoptosis, Associated Proteins, Cancer, Cell Biology, Growth Factors, Growth Factors/Hormones, Intracellular, Neurogenesis, Neurology Process, Neuroscience, Signal Transduction