ELISA/assay

Mouse KLK1/Kallikrein 1 ELISA Kit PicoKine®

EK1586

96 wells/kit, with removable strips.

369美元

Mouse KLK1/Kallikrein 1 ELISA Kit PicoKine®

96 wells/kit, with removable strips.

369美元

Mouse KLK1 / Kallikrein 1 / Tissue kallikrein ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Klk1 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 12pg/ml.

小鼠

酶联免疫吸附测定

Klk1

P15947

Expression system for standard: NS0; Immunogen sequence: I25-D261

There is no detectable cross-reactivity with other relevant proteins.

62.5 pg/ml - 4,000 pg/ml

<12 pg/ml

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

单克隆抗体来自大鼠, 多克隆抗体来自山羊

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

激肽释放酶1

Kallikrein-1;3.4.21.35;Glandular kallikrein K1;KAL-B;Renal kallikrein;Tissue kallikrein-6;mGK-6;Klk1;Klk-6, Klk6;

激肽释放酶1

28775分子量

Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.

Kallikrein-1, also known as tissue kallikrein, is a protein that in humans is encoded by the KLK1 gene. This serine protease generates Lys-bradykinin by specific proteolysis of kininogen-1. KLK1 is a member of the peptidase S1 family. Its gene is mapped to 19q13.3. In all, it has got 262-amino acids which contain a putative signal peptide, followed by a short activating peptide and the protease domain. The protein is mainly found in kidney, pancreas, and salivary gland, showing a unique pattern of tissue-specific expression relative to other members of the family. KLK1 is implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers.

Angiogenesis, Cancer, Cardiovascular, Cell Biology, Cytoskeleton / Ecm, Ecm Enzymes, Extracellular Matrix, Invasion/Microenvironment, Proteolysis / Ubiquitin, Proteolytic Enzymes, Serum Proteins, Signal Transduction