ELISA/assay

Mouse IL-23R/Interleukin-23 receptor ELISA Kit PicoKine®

EK1613

96 wells/kit, with removable strips.

369美元

Mouse IL-23R/Interleukin-23 receptor ELISA Kit PicoKine®

96 wells/kit, with removable strips.

369美元

Mouse IL-23R ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Il23r in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

小鼠

酶联免疫吸附测定

Il23r

Q8K4B4

Expression system for standard: NS0; Immunogen sequence: I25-I373

There is no detectable cross-reactivity with other relevant proteins.

78 pg/ml - 5,000 pg/ml

<10 pg/ml

cell culture supernatants, serum and plasma (heparin, EDTA)

a单克隆抗体来自大鼠, a生物素多克隆抗体来自山羊

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

白细胞介素23受体

白细胞介素23受体;IL-23受体;IL-23R;Il23r;

Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis (By similarity).

Cell membrane ; Single-pass type I membrane protein .

Expressed by Th1, Th2 and dendritic cells.

Interleukin-23 subunit alpha is a protein that in humans is encoded by the IL23A gene. The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.

Cell Type Markers, Cytokines, Epigenetics and Nuclear Signaling, Immunoglobulins, Immunology, Innate Immunity, Interleukins, Nuclear Signaling, Nuclear Signaling Pathways, Receptors, Signal Transduction, Signaling Pathway