ELISA/assay

Human Contactin-4 ELISA Kit PicoKine®

EK1780

96 wells/kit, with removable strips.

369美元

Human Contactin-4 ELISA Kit PicoKine®

96 wells/kit, with removable strips.

369美元

Human Contactin-4 ELISA Kit PicoKine® (96 Tests). Quantitate Human CNTN4 in cell culture supernatants, serum and plasma (heparin, EDTA, citrate). Sensitivity: 50pg/ml.

人类

酶联免疫吸附测定

CNTN4

Q8IWV2

Expression system for standard: NS0; Immunogen sequence: D19-S1000

There is no detectable cross-reactivity with other relevant proteins.

312 pg/ml - 20,000 pg/ml

<50 pg/ml

cell culture supernatants, serum and plasma (heparin, EDTA, citrate)

a单克隆抗体来自小鼠, a生物素多克隆抗体来自山羊

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

contactin 4

Contactin-4; Brain-derived immunoglobulin superfamily protein 2; BIG-2; CNTN4

Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity. May be involved in synaptogenesis.

Secreted. Cell membrane. GPI-anchor.

Mainly expressed in brain. Highly expressed in cerebellum and weakly expressed in corpus callosum, caudate nucleus, amygdala and spinal cord. Also expressed in testis, pancreas, thyroid, uterus, small intestine and kidney. Not expressed in skeletal muscle. Isoform 2 is weakly expressed in cerebral cortex.

Contactin-4 is a protein that in humans is encoded by the CNTN4 gene. It is mapped to 3p26.3-p26.2. This gene encodes a member of the contactin family of immunoglobulins. Contactins are axon-associated cell adhesion molecules that function in neuronal network formation and plasticity. The encoded protein is a glycosylphosphatidylinositol-anchored neuronal membrane protein that may play a role in the formation of axon connections in the developing nervous system. Deletion or mutation of this gene may play a role in 3p deletion syndrome and autism spectrum disorders. Alternative splicing results in multiple transcript variants.