ELISA/assay

Human Langerin/CD207 ELISA Kit PicoKine®

EK2162

96 wells/kit, with removable strips.

369美元

Human Langerin/CD207 ELISA Kit PicoKine®

96 wells/kit, with removable strips.

369美元

Human Langerin/CD207 ELISA Kit PicoKine® (96 Tests). Quantitate Human CD207 in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 10 pg/ml.

人类

酶联免疫吸附测定

CD207

Q9UJ71

Expression system for standard: NS0; Immunogen sequence: P65-P328

There is no detectable cross-reactivity with other relevant proteins.

156 pg/ml - 10,000 pg/ml

<10 pg/ml

cell culture supernatants, serum and plasma (heparin, EDTA)

a单克隆抗体来自小鼠, a生物素多克隆抗体来自山羊

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Langerin (CD207) is a type II transmembrane protein which is encoded by the CD207 gene in humans. The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.