ELISA/assay

Caspase 3 (Phospho-Ser150) Colorimetric Cell-Based ELISA Kit

EKC2227

1 kit, containing 2 plates and all necessary reagents

480美元

Caspase 3 (Phospho-Ser150) Colorimetric Cell-Based ELISA Kit

1 kit, containing 2 plates and all necessary reagents

480美元

The Caspase 3 (Phospho-Ser150) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Caspase 3 (Phospho-Ser150) protein expression profile in cells. The kit can be used for measuring the relative amounts of Caspase 3 (Phospho-Ser150) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Caspase 3 (Phospho-Ser150).

人类, 小鼠, 大鼠

酶联免疫吸附测定

CASP3

P42574

> 5000 Cells

>5000 cells

4°C/6 Months

胱氨酸-天冬氨酸蛋白酶3

Caspase-3;CASP-3;3.4.22.56;Apopain;Cysteine protease CPP32;CPP-32;Protein Yama;SREBP cleavage activity 1;SCA-1;Caspase-3 subunit p17;Caspase-3 subunit p12;CASP3;CPP32;

31608分子量

Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly (ADP-ribose) polymerase (PARP) at a '216-Asp- -Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop- helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.

细胞质

Highly expressed in lung, spleen, heart, liver and kidney. Moderate levels in brain and skeletal muscle, and low in testis. Also found in many cell lines, highest expression in cells of the immune system.