ELISA/assay

Androgen Receptor (Phospho-Tyr363) Colorimetric Cell-Based ELISA Kit

EKC2586

1 kit, containing 2 plates and all necessary reagents

480美元

Androgen Receptor (Phospho-Tyr363) Colorimetric Cell-Based ELISA Kit

1 kit, containing 2 plates and all necessary reagents

480美元

The Androgen Receptor (Phospho-Tyr363) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Androgen Receptor (Phospho-Tyr363) protein expression profile in cells. The kit can be used for measuring the relative amounts of Androgen Receptor (Phospho-Tyr363) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Androgen Receptor (Phospho-Tyr363).

人类, 小鼠, 大鼠

酶联免疫吸附测定

AR

P10275

> 5000 Cells

>5000 cells

4°C/6 Months

雄激素受体

Androgen receptor;Dihydrotestosterone receptor;Nuclear receptor subfamily 3 group C member 4;AR;DHTR, NR3C4;

99188分子量

Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.

Nucleus . Cytoplasm . Predominantly cytoplasmic in unligated form but translocates to the nucleus upon ligand-binding. Can also translocate to the nucleus in unligated form in the presence of RACK1.

Isoform 2 is mainly expressed in heart and skeletal muscle (PubMed:15634333). Isoform 3 is expressed by basal and stromal cells of prostate (at protein level) (PubMed:19244107).