产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
ELISA/assay
产品名称 :
Human CCL18/PARC ELISA Kit EZ-Set™ (DIY Antibody Pairs)
目录 :
EZ0686
规格 :
For 5 plates, 96 wells each
价格 :
215美元
文章摘录数: 2
参考文献
Cai M, Bonella F, He X, Sixt S, Sarria R, Guzman J, et al. CCL18 in serum, BAL fluid and alveolar macrophage culture supernatant in interstitial lung diseases. Respir Med. 2013;107:1444-52 pubmed 出版商
Wu J, Liu X, Wang Y. Predictive value of preoperative serum CCL2, CCL18, and VEGF for the patients with gastric cancer. BMC Clin Pathol. 2013;13:15 pubmed 出版商
图像
图像 1 :
武汉博士德生物工程有限公司 EZ0686 图像 1
Human CCL18/PARC EZ Set ELISA Kit standard curve
产品信息
SKU号 :
EZ0686
产品名称 :
Human CCL18/PARC ELISA Kit EZ-Set™ (DIY Antibody Pairs)
规格 :
For 5 plates, 96 wells each
价格 :
215美元
描述 :
Human CCL18/PARC ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development). Quantitate Human CCL18 in cell culture supernatants and serum. Sensitivity: 10 pg/ml. Product Features: Your ideal low cost ELISA solution. EZ Set™ ELISA kit contains the necessary core reagents develop and run the ELISA, including ELISA-optimized matched antibody pairs, recombinant protein standards, and HRP conjugated Avidin-Biotin-Complex (ABC). One kit is sufficient for developing 5 plates (96 well format). EZ Set™ ELISAs are ideal for experienced ELISA users on a budget and great for exploratory work--a fast and easy way to identify the relevant protein targets of interest/relevance to your studies.
反应物种 :
人类
应用 :
酶联免疫吸附测定
基因名称 :
CCL18
UniProt数据库编号 :
P55774
免疫原 :
Expression system for standard: E.coli; Immunogen sequence: A21-A89
交叉活性 :
There is no detectable cross-reactivity with other relevant proteins.
试验范围 :
7.8 pg/ml - 500 pg/ml
敏感性 :
<10 pg/ml
样品类型 :
cell culture supernatants and serum
储存 :
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
基因全称 :
C-C motif chemokine 18
同义词 :
C-C motif chemokine 18;Alternative macrophage activation-associated CC chemokine 1;AMAC-1;CC chemokine PARC;Dendritic cell chemokine 1;DC-CK1;Macrophage inflammatory protein 4;MIP-4;Pulmonary and activation-regulated chemokine;Small-inducible cytokine A18;CCL18 (1-68);CCL18 (3-69);CCL18 (4-69);CCL18;AMAC1, DCCK1, MIP4, PARC, SCYA18;
蛋白名 :
C-C motif chemokine 18
分子量 :
9849分子量
Protein Function :
Chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. May be involved in B-cell migration into B-cell follicles in lymph nodes. Attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses.
Subcellular Localization :
Secreted.
组织特异性 :
Expressed at high levels in lung, lymph nodes, placenta, bone marrow, dendritic cells present in germinal centers and T-cell areas of secondary lymphoid organs and macrophages derived from peripheral blood monocytes. Not expressed by peripheral blood monocytes and a monocyte-to-macrophage differentiation is a prerequisite for expression. Expressed in synovial fluids from patients with rheumatoid and septic arthritis and in ovarian carcinoma ascitic fluid.
Sequence Similarities :
Belongs to the intercrine beta (chemokine CC) family.
背景 :
Chemokine (C-C motif) ligand 18 (CCL18) is a small cytokine belonging to the CC chemokine family that was previously called PARC (pulmonary and activation-regulated chemokine). CCL18 is approximately 60% identical in amino acid sequence to CCL3. By analysis of a previously mapped CCL18 from 17q11.2, it is determined that the PARC gene is located within 1 of the 2 clusters of CC chemokine genes in this region. It is expressed at high levels in lung and at lower levels in certain lymphoid tissues, such as the lymph nodes, and is chemotactic for activated T cells and nonactivated lymphocytes. Beside, CCL18 recruits Th2 cells and basophils and may play a predominant role in allergic asthma.
研究种类 :
Cancer, Chemokines, Immunology, Innate Immunity, Oncoproteins, Tumor Biomarkers
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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