ELISA/assay

Mouse IL-23R ELISA Kit EZ-Set™ (DIY Antibody Pairs)

EZ1613

For 5 plates, 96 wells each

255美元

Mouse IL-23R ELISA Kit EZ-Set™ (DIY Antibody Pairs)

For 5 plates, 96 wells each

255美元

Mouse IL-23R ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development). Quantitate Mouse Il23r in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 10 pg/ml. Product Features: Your ideal low cost ELISA solution. EZ Set™ ELISA kit contains the necessary core reagents develop and run the ELISA, including ELISA-optimized matched antibody pairs, recombinant protein standards, and HRP conjugated Avidin-Biotin-Complex (ABC). One kit is sufficient for developing 5 plates (96 well format). EZ Set™ ELISAs are ideal for experienced ELISA users on a budget and great for exploratory work--a fast and easy way to identify the relevant protein targets of interest/relevance to your studies.

小鼠

酶联免疫吸附测定

Il23r

Q8K4B4

Expression system for standard: NS0; Immunogen sequence: I25-I373

There is no detectable cross-reactivity with other relevant proteins.

78 pg/ml - 5,000 pg/ml

<10 pg/ml

cell culture supernatants, serum and plasma (heparin, EDTA)

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

白细胞介素23受体

白细胞介素23受体;IL-23受体;IL-23R;Il23r

Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis (By similarity).

Cell membrane; Single-pass type I membrane protein.

Expressed by Th1, Th2 and dendritic cells.

Interleukin-23 subunit alpha is a protein that in humans is encoded by the IL23A gene. The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.

Cell Type Markers, Cytokines, Epigenetics and Nuclear Signaling, Immunoglobulins, Immunology, Innate Immunity, Interleukins, Nuclear Signaling, Nuclear Signaling Pathways, Receptors, Signal Transduction, Signaling Pathway