抗体

Anti-human CD38 Monoclonal Antibody Unconjugated, Flow Validated

FC00193

100µg, 500µg

79美元

单克隆

小鼠

nonconjugated

OKT10

Enabled

Anti-human CD38 Monoclonal Antibody Unconjugated, Flow Validated

一抗, 单克隆抗体, 流式细胞仪抗体

CD38

79美元

100微克/$79 500微克/$320 25试验/$79

单克隆

OKT10

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

No

PBS, pH7.2, 0.09% NaN3

Monoclonal clone# G2 antibody for CD38 detection. Host: Mouse.Size: 100µg, 500µg. Tested applications: Flow Cytometry. Reactive species: Human. CD38 information: Molecular Weight: 34328 MW; Subcellular Localization: Membrane; Single-pass type II membrane protein; Tissue Specificity: Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma.

Mouse Monoclonal Anti-human CD38 Unconjugated, designed for Flow Cytometry and validated by Flow Cytometry using Human cells.

Introduction . CD38 is a type II transmembrane glycoprotein of 45 kDa with a protein core of 35 kDa. The CD38 antigen is expressed on essentially all pre-B lymphocytes, plasma cells, and thymocytes. It is also present on activated T lymphocytes, natural killer (NK) lymphocytes, myeloblasts, and erythroblasts. The antigen is expressed during the early stages of T- and B-lymphocyte differentiation, is lost during the intermediate stages of maturation, and then reappears during the final stages of maturation. The CD38 antigen is expressed on 90% of CD34+ cells, and is not expressed on pluripotent stem cells. Coexpression of CD38 antigen on CD34+ cells indicates lineage commitment of those cells. CD38 is a counter-receptor of CD31. It is also expressed in T- and B-acute lymphoblastic leukemia (ALL), Burkitts lymphoma, multiple myeloma, acute myeloid leukemia (AML), and chronic lymphocytic leukemia (CLL). The OKT10 antibody directed against human CD38 antigen. . This antibody is routinely tested by flow cytometric analysis. Flow cytometry and other applications were tested during antibody development by CapricoBio or are reported in the literature. Application Information . Each lot of this antibody has been quality control tested by flow cytometric analysis of human PBMCs. For flow cytometric staining, the recommended use of this antibody is 0.5ug per 1x106 cells in 100ul of staining volume or 0.1ml whole blood followed by a secondary florescent conjugated anti-mouse antibody. However, it is strongly suggested that the antibody reactivity be empirically titrated for optimal performance in the application of interest.

100µg, 500µg

P28907

小鼠

Liquid

蛋白质A纯化

4 C。 不冻结

IgG1, k

5ul per sample

User need to optimize the dilution ratio for this antibody

流式细胞仪

人类

Lymphocytes gated PBMCs stained with purified anti-human CD38 (clone OKT-10) followed by Goat anti-mouse IgG (H+L) Alexa Fluor 488 (red histogram). PBMCs monocytes stained with only Goat antimouse IgG (H+L) Alexa Fluor 488 (Blue histogram).

sc 15362 sc 374650 sc 7049 sc 51726 sc 7048 sc 18858 sc 7047 sc 59028 sc 7325 sc 70655 sc 70654

Adaptive Immunity, B Cells, Cancer, Cancer Metabolism, Hematopoietic Progenitors, Immunology, Lymphoid, Metabolism, Metabolism Processes, Myeloid, Pathways And Processes, Response To Hypoxia, Stem Cells, Surface Molecules, T Lymphocytic Lineage

ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1;3.2.2.6;2'-phospho-ADP-ribosyl cyclase;2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase;2.4.99.20;2'-phospho-cyclic-ADP-ribose transferase;ADP-ribosyl cyclase 1;ADPRC 1;Cyclic ADP-ribose hydrolase 1;cADPr hydrolase 1;T10;CD38;CD38;

ADP的核糖酸环化酶/环磷酸腺苷核糖水解酶1

34328分子量

Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.

Membrane; Single-pass type II membrane protein.

Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma.

ADP的核糖酸环化酶/环磷酸腺苷核糖水解酶1

2/6/19 22:57