Anti-human CD2 Monoclonal Antibody Biotin Conjugated, Flow Validated | 武汉博士德生物工程有限公司 FC00570-Biotin 产品信息

产品简要

公司名称 :

武汉博士德生物工程有限公司

产品类型 :

抗体

产品名称 :

Anti-human CD2 Monoclonal Antibody Biotin Conjugated, Flow Validated

FC00570生物素

规格 :

100Âµg

价格 :

158美元

克隆性 :

单克隆

宿主 :

小鼠

共轭标签 :

生物素

克隆名称 :

OKT11

反应物种 :

人类

应用 :

流式细胞仪

更多信息或购买 :

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图像

图像 1 :

Lymphocytes gated PBMCs stained with anti-human CD2 Biotin (clone OKT 11) (red histogram) followed by a secondary staining with SA-PE. PBMCs stained with isotype IgG1 biotin followed by a secondary staining with SA-PE (Blue histogram) was used as control.

产品信息

SKU号 :

FC00570生物素

状态 :

Enabled

名称 :

Anti-human CD2 Monoclonal Antibody Biotin Conjugated, Flow Validated

目录名称 :

一抗, 单克隆抗体, 流式细胞仪抗体

基因名称 :

CD2

价格 :

158美元

price various sizes :

100微克/$158

克隆性 :

单克隆

克隆编号 :

OKT11

浓度 :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

共轭标签 :

生物素

contents :

PBS, pH7.2, 0.09% NaN3

描述 :

Monoclonal clone# G2 antibody for CD2 detection. Host: Mouse.Size: 100Âµg. Tested applications: Flow Cytometry. Reactive species: Human. CD2 information: Molecular Weight: 39448 MW; Subcellular Localization: Membrane; Single-pass type I membrane protein.

short description :

Mouse Monoclonal Anti-human CD2 Biotin Conjugated, designed for Flow Cytometry and validated by Flow Cytometry using Human cells.

description1 :

Introduction . CD2 is a 50kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. It is a specific marker for T lymphocytes, natural killer cells, thymic B cell subsets, and some antigen presenting cells. CD2 interacts with CD58 (LFA-3) and CD48 to mediate cell adhesion and induce co-stimulatory signals in T lymphocytes. . This antibody is routinely tested by flow cytometric analysis. Flow cytometry and other applications were tested during antibody development by CapricoBio or are reported in the literature. Application Information . Each lot of this antibody has been pre-titrated and tested by flow cytometric analysis of human PBMCs such that 5ul of this product is sufficient for staining of 1 million cells in a 100ul staining volume or 100ul of whole blood. This biotin conjugated antibody can be easily detected by any fluorochrome conjugated streptavidin. It is recommended that antibody reactivity be empirically titrated for optimal performance in the application of interest.

规格 :

100Âµg

UniProt数据库编号 :

P06729

宿主 :

小鼠

形式 :

Liquid

纯化 :

蛋白质A纯化

储存 :

4 C。不冻结

抗体亚型 :

IgG1, k

敏感性 :

5ul per sample

应用细节 :

User need to optimize the dilution ratio for this antibody

应用 :

流式细胞仪

反应物种 :

人类

图像标记 :

背景 :

CD2(cluster of differentiation 2) is a cell adhesion molecule found on the surface of T cells and natural killer(NK) cells. It has also been called T-cell surface antigen T11/Leu-5, LFA-2, LFA-3 receptor, erythrocyte receptor and rosette receptor. Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it. It is one of the earliest T-cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B lymphocytes. Due to its structural characteristics, CD2 is a member of the immunoglobulin superfamily; it possesses two immunoglobulin-like domains in its extracellular portionThe localization of CD2 to 1p13 was established by in situ hybridization. By Southern blotting of DNA from a panel of somatic cell hybrids, Clayton et al.(1988) assigned the CD2 gene to human chromosome 1 and murine chromosome 3.CD2 interacts with other adhesion molecules, such as lymphocyte function-associated antigen-3(LFA-3/CD58) in humans, or CD48 in rodents, which are expressed on the surfaces of other cells. With the use of transgenic mice, such an LCR was identified within the 3-prime flanking region of the human CD2 gene.

competitor equivalent skus :

sc 28807 sc 19639 sc 53038 sc 53036 sc 13531 sc 20046 sc 65247 sc 19640 sc 81732 sc 19638 sc 7318 sc 28808 sc 365017 sc 6987 sc 136974 sc 18907 sc 53823

研究种类 :

Adaptive Immunity, Hematopoietic Progenitors, Immunology, Lymphoid, Myeloid, Stem Cells, T Cells, T Lymphocytic Lineage

同义词 :

T-cell surface antigen CD2;Erythrocyte receptor;LFA-2;LFA-3 receptor;Rosette receptor;T-cell surface antigen T11/Leu-5;CD2;CD2;SRBC;

基因全称 :

T细胞表面抗原CD2

分子量 :

39448分子量

protein function :

CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T- cells, the cytoplasmic domain is implicated in the signaling function.

subcellular localization :

Membrane; Single-pass type I membrane protein.

蛋白名 :

T细胞表面抗原CD2

更新 :

2/6/19 22:57

更多信息或购买 :

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