抗体

Anti-human CD71 Antibody Unconjugated, Flow Validated

FC00591

100µg, 500µg

129;516美元

单克隆

小鼠

nonconjugated

OKT9

Anti-human CD71 Antibody Unconjugated, Flow Validated

129;516美元

Human acute lymphoblastic leukemia cells

Liquid

小鼠

PBS, pH7.2, 0.09% NaN3

蛋白质A纯化

单克隆

Mouse Monoclonal Anti-human CD71 Unconjugated, designed for Flow Cytometry and validated by Flow Cytometry using Human cells.

100µg, 500µg

人类

流式细胞仪

CD71 is also known as transferrin receptor(TFRC). Nikinmaa and Schroder(1987) concluded that p90 and TFRC are the same protein: studies using monoclonal antibodies indicated that exhaustive precipitation of radioactively labeled lysates with one antibody removed all activity of lysates with the other. Peptide maps of antigens recognized with both antibodies showed great similarity and indicated that both antibodies react with the same antigen, the human transferrin receptor, but with different antigenic sites of the molecule.TFR is assigned to chromosome 3.

OKT9

转铁蛋白受体蛋白1

转铁蛋白受体

IgG1, k

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.

转铁蛋白受体蛋白1

cardiovascular blood serum proteins immunology cell type markers non-lineage stem cells neural stem cells surface molecules hematopoietic progenitors lymphoid b lymphocytic lineage t lymphocytic lineage myeloid erythrocytic lineage cancer cancer metabolism response to hypoxia metabolism pathways and processes metabolism processes types of disease

4。 不冻结

Cell membrane ; Single-pass type II membrane protein . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Transferrin receptor protein 1;TR;TfR;TfR1;Trfr;T9;p90;CD71;Transferrin receptor protein 1, serum form;sTfR;TFRC;

P02786