抗体

Anti-human CD16 Monoclonal Antibody PE Conjugated, Flow Validated

FC01408-PE

25试验, 100试验, 200试验

89美元

单克隆

小鼠

PE

3G8

Enabled

Anti-human CD16 Monoclonal Antibody PE Conjugated, Flow Validated

一抗, 单克隆抗体, 流式细胞仪抗体

FCGR3A

89美元

25试验/$89 100试验/$199 200试验/$319

单克隆

3G8

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

PE

PBS, pH7.2, 0.09% NaN3和0.2%(w/v)BSA

Monoclonal clone# G2 antibody for CD16/FCGR3A detection. Host: Mouse.Size: 25 Tests, 100 Tests, 200 Tests. Tested applications: Flow Cytometry. Reactive species: Human. CD16/FCGR3A information: Molecular Weight: 29089 MW; Subcellular Localization: Cell membrane ; Single-pass type I membrane protein . Secreted. Exists also as a soluble receptor; Tissue Specificity: Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts.

Mouse Monoclonal Anti-human CD16 PE Conjugated, designed for Flow Cytometry and validated by Flow Cytometry using Human cells.

Introduction . CD16 (3G8) binds to the 50-65 kDa transmembrane protein of IgG FcgammaRIII, an surface antigen commonly associated with human NK cells. Besides surface expression on NK cells, it is also expressed on activated monocytes, macrophages, on neutrophils and placental trophoblasts in humans. CD16 binds aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC). 3G8 is also useful in experiments related to immunohistochemical staining, immunoprecipitation, NK cell proliferation, blocking of phagocytosis and blocking of immunoglobulin binding tthrough FcgammaRIII. . This antibody is routinely tested by flow cytometric analysis. Flow cytometry and other applications were tested during antibody development by CapricoBio or are reported in the literature. Application Information . Each lot of this antibody has been pre-titrated and tested by flow cytometric analysis of human PBMCs such that 5ul of this product is sufficient for staining of 1 million cells in a 100ul staining volume or 100ul of whole blood. It is recommended that antibody reactivity be empirically titrated for optimal performance in the application of interest.

25试验, 100试验, 200试验

P08637

小鼠

Human peripheral blood T lymphocytes

Liquid

蛋白质A纯化

4 C and protect from prolonged exposure to light. Do not freeze.

IgG1, k

5ul per sample

Flow Cytometry, 5ul is enough to stain 1 million PBMCs or 100ul whole blood sample.

流式细胞仪

人类

Anti-human CD16 PE Conjugated, Flow Validated

Cell Type Markers, Hematopoietic Progenitors, Immunology, Lymphoid, Myeloid, Nk Cells, Stem Cells

Low affinity immunoglobulin gamma Fc region receptor III-A;CD16a antigen;Fc-gamma RIII-alpha;Fc-gamma RIII;Fc-gamma RIIIa;FcRIII;FcRIIIa;FcR-10;IgG Fc receptor III-2;CD16a;FCGR3A;CD16A, FCG3, FCGR3, IGFR3;

Low affinity immunoglobulin gamma Fc region receptor III-A

29089分子量

Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.

Cell membrane ; Single-pass type I membrane protein . Secreted. Exists also as a soluble receptor.

Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts.

Low affinity immunoglobulin gamma Fc region receptor III-A

2/6/19 22:57