抗体

抗甲1 SERPINA1抗体过氧化物酶 共轭标签

H00720

100微克

488美元

多克隆

domestic goat

HRP

多克隆

抗甲1 SERPINA1抗体过氧化物酶 共轭标签

488美元

100微克

多克隆

山羊

HRP

人类

免疫印迹

免疫印迹, 1:500 - 1:2, 500, 人类

Boster Bio Anti-Alpha-1-Trypsin SERPINA1 Antibody Peroxidase Conjugated catalog # H00720. Tested in WB applications. This antibody reacts with Human.

1.0 mg/mL by UV absorbance at 280 nm

SERPINA1

P01009

液体

甲1

Alpha-1-antitrypsin; Alpha-1 protease inhibitor; Alpha-1-antiproteinase; Serpin A1; Short peptide from AAT; SPAAT; SERPINA1; AAT, PI; PRO0684, PRO2209;

46737分子量

Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.

Secreted. Endoplasmic reticulum. The S and Z allele are not secreted effectively and accumulate intracellularly in the endoplasmic reticulum.

Ubiquitous. Expressed in leukocytes and plasma.

SERPINA1 is also known as PI, A1A or AAT. This gene is mapped to 14q32.1. The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene.

Apoptosis, Cancer, Cancer Metabolism, Cardiovascular, Cell Biology, Intracellular, Kinases, Metabolism, Metabolism Processes, Pathways And Processes, Protease Inhibitors, Proteolysis / Ubiquitin, Response To Hypoxia, Serum Proteins