产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
抗体
产品名称 :
抗肿瘤坏死因子甲(肿瘤坏死因子α)单克隆抗体
目录 :
M00002
规格 :
100 ug/vial
价格 :
299美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
克隆名称 :
TNF706 + P/T2
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫组化
图像
图像 1 :
武汉博士德生物工程有限公司 M00002 图像 1
Formalin-fixed, paraffin-embedded human Erdheim Chester disease (also known as polyostotic sclerosing histiocytosis) stained withTNF alpha Monoclonal Antibody (TNF706 + P/T2).
产品信息
SKU号 :
M00002
状态 :
Enabled
名称 :
抗肿瘤坏死因子甲(肿瘤坏死因子α)单克隆抗体
目录名称 :
一抗, 单克隆抗体, 免疫组化免疫细胞化学IF抗体
基因名称 :
肿瘤坏死因子
价格 :
299美元
price various sizes :
20ug sample size / $99 100ug / $299 100ug+Free HRP Secondary BA1050 / $299 100ug+Free Biotin Secondary BA1001 / $299
克隆性 :
单克隆
克隆编号 :
TNF706 + P/T2
浓度 :
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
共轭标签 :
No
contents :
Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
描述 :
Mouse Monoclonal Antibody [Clone TNF706 + P/T2] antibody for TNF ALPHA/TNF detection. Host: Mouse.Size: 100ug/vial. Tested applications: IF. Reactive species: Canine. TNF ALPHA/TNF information: Molecular Weight: 25644 MW; Subcellular Localization: Cell membrane ; Single-pass type II membrane protein .
short description :
抗肿瘤坏死因子甲(肿瘤坏死因子α)抗体
规格 :
100 ug/vial
sample size available :
20ug for $99, contact us for details
UniProt数据库编号 :
P01375
宿主 :
小鼠
免疫原 :
Recombinant N-terminal fragment of human TNF-? (TNF706); Peptide corresponding to aa115-130 of human TNF-? (P/T2)
形式 :
Liquid
储存 :
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.
应用细节 :
Immunohistology (Formalin-paraffin) (2-4ug/ml for 30 min at RT). Immunofluorescence (1-2ug/ml)
应用 :
免疫组化
反应物种 :
狗, 人类, 小鼠, 兔, 大鼠
图像标记 :
Formalin-fixed, paraffin-embedded human Erdheim Chester disease (also known as polyostotic sclerosing histiocytosis) stained withTNF alpha Monoclonal Antibody (TNF706 + P/T2).
研究种类 :
Atherosclerosis, Cancer, Cardiovascular, Cytokines, Growth Factors, Growth Factors/Hormones, Immunology, Innate Immunity, Metabolism, Signal Transduction, Tnf Superfamily, Vascular Inflammation
同义词 :
Tumor necrosis factor;Cachectin;TNF-alpha;Tumor necrosis factor ligand superfamily member 2;TNF-a;Tumor necrosis factor, membrane form;N-terminal fragment;NTF;Intracellular domain 1;ICD1;Intracellular domain 2;ICD2;C-domain 1;C-domain 2;Tumor necrosis factor, soluble form;TNF;TNFA, TNFSF2;
基因全称 :
肿瘤坏死因子
分子量 :
25644分子量
protein function :
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Impairs regulatory T-cells (Treg) function in individuals with rheumatoid arthritis via FOXP3 dephosphorylation. Upregulates the expression of protein phosphatase 1 (PP1), which dephosphorylates the key 'Ser-418' residue of FOXP3, thereby inactivating FOXP3 and rendering Treg cells functionally defective (PubMed:23396208). Key mediator of cell death in the anticancer action of BCG-stimulated neutrophils in combination with DIABLO/SMAC mimetic in the RT4v6 bladder cancer cell line (PubMed:22517918).
subcellular localization :
Cell membrane ; Single-pass type II membrane protein .
更新 :
4/9/19 19:48
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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