抗体

抗PR(孕激素受体)PGR兔单克隆抗体, Clone#RM357

M00541-3

100微升

399美元

单克隆

domestic rabbit

未共轭

RM357

免疫印迹, 免疫组化

抗PR(孕激素受体)PGR兔单克隆抗体, Clone#RM357

399美元

100微升

单克隆

RM357

兔

人类

免疫印迹, 免疫组化

免疫组化(免疫组化):1:100-1:200稀释;免疫印迹(免疫印迹):1:1000-1:2000稀释

Boster Bio Anti-PR (Progesterone Receptor) PGR Rabbit Monoclonal Antibody, Clone#RM357 catalog # M00541-3. Tested in IHC, WB applications. This antibody reacts with Human.

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

PGR

P06401

A peptide corresponding to C-terminus of human Progesterone Receptor.

50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

孕激素受体

Progesterone receptor; PR; Nuclear receptor subfamily 3 group C member 3; PGR; NR3C3;

98981分子量

The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Depending on the isoform, progesterone receptor functions as transcriptional activator or repressor.

Nucleus. Cytoplasm. Nucleoplasmic shuttling is both homone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G (1) and G (2)/M phases.

In reproductive tissues the expression of isoform A and isoform B varies as a consequence of developmental and hormonal status. Isoform A and isoform B are expressed in comparable levels in uterine glandular epithelium during the proliferative phase of the menstrual cycle. Expression of isoform B but not of isoform A persists in the glands during mid-secretory phase. In the stroma, isoform A is the predominant form throughout the cycle. Heterogeneous isoform expression between the glands of the endometrium basalis and functionalis is implying region- specific responses to hormonal stimuli.

Cancer, Domain Families, Endocrine System, Epigenetics and Nuclear Signaling, Neuroscience, Nuclear Hormone Receptors, Nuclear Receptors, Nuclear Signaling Pathways, Signal Transduction, Signaling Pathway, Transcription, Tumor Biomarkers, Zinc Finger