产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
抗体
产品名称 :
抗细胞角蛋白肽18 KRT18抗体(单克隆, CY-90)
目录 :
MA1026
规格 :
100μg/vial
价格 :
315美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
CY-90
反应物种 :
人类, 大鼠
应用 :
免疫印迹, 免疫组化
更多信息或购买 :
图像
图像 1 :
Anti-Cytokeratin Peptide 18 antibody (monoclonal), MA1026, Western blotting. WB: MCF-7 Cell Lysate
图像 2 :
Anti-Cytokeratin Peptide 18 antibody (monoclonal), MA1026, IHC(P). IHC(P): Human Mammary Cancer Tissue
图像 3 :
Anti-Cytokeratin Peptide 18 antibody (monoclonal), MA1026, IHC(P). IHC(P): Human Rectal Cancer Tissue
产品信息
SKU号 :
MA1026
产品名称 :
抗细胞角蛋白肽18 KRT18抗体(单克隆, CY-90)
价格 :
315美元
规格 :
100μg/vial
克隆性 :
单克隆
克隆编号 :
CY-90
宿主 :
小鼠
反应物种 :
人类, 大鼠
应用(s) :
免疫组化, 免疫印迹
应用细节 :
Immunohistochemistry (Paraffin-embedded Section), 1-2µg/ml, Human, rat, By Heat.
Immunohistochemistry (Frozen Section), 0.5-2µg/ml, Human, rat Western blot, 0.5-1µg/ml, Human, rat.
应用注释 :
Other applications have not been tested.
Optimal dilutions should be determined by end users.
描述 :
Boster Bio Anti-Cytokeratin Peptide 18 KRT18 Antibody (Monoclonal, CY-90) catalog # MA1026. Tested in IHC, WB applications. This antibody reacts with Human, Rat.
浓度 :
Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.
基因名称 :
KRT18
UniProt数据库编号 :
Q5BJY9
免疫原 :
The human epidermal carcinoma A-431 and MCF-7 human breast cancer cell lines.
形式 :
冻干
Contents :
Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
纯化 :
腹水
交叉活性 :
No cross reactivity with other proteins
抗体亚型 :
小鼠IgG1
储存 :
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
重组 :
Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
基因全称 :
Keratin, type I cytoskeletal 18
同义词 :
Keratin, type I cytoskeletal 18; Cytokeratin-18; CK-18; Keratin-18; K18; Krt18 ; Krt1-18 ;
蛋白名 :
Keratin, type I cytoskeletal 18
分子量 :
47761分子量
Protein Function :
When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection (By similarity). Involved in the uptake of thrombin-antithrombin complexes by hepatic cells.
Subcellular Localization :
Nucleus matrix. Nucleus, nucleolus. Cytoplasm.
组织特异性 :
Expressed on the plasma membrane of hepatocytes and in the narrow apical portions of supporting cells in the vomeronasal sensory epithelium. Detected in the type III alveolar cells of the lung, in the proliferative crypt epithelium of the small intestine and in the older intragemmal cells of the tongue.
Recommended Detection Systems :
Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P) and IHC(F).
Sequence Similarities :
Belongs to the intermediate filament family.
背景 :
Intermediate filaments (IFs) are a structurally related family of cellular proteins that appear to be intimately involved with the cytoskeleton. Human keratin 18 (KRT18) and the homologous mouse Endo B are type I IF protein subunits whose expression is restricted in adults to a variety of simple epithelial tissues. The KRT18 gene is 3,791 bp long and the keratin 18 protein is coded for by 7 exons. The K18 gene is 3791 bp in length and the K18 protein is coded for by seven exons. By Southern blotting using the genomic DNA PCR product, the gene for keratin 18 is assigned to chromosome 12. Mutation of human keratin 18 in association with cryptogenic cirrhosis.
研究种类 :
Cell Type Markers, Class I, Cytoskeleton, Cytoskeleton / Ecm, Ecm Proteins, Extracellular Matrix, Intermediate Filaments, Microtubules, Signal Transduction, Structures, Tumor Associated
更多信息或购买 :
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn925.485.4527
公司总部: 美国
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