抗体

抗c Myc抗体(单克隆, 9E10)

MA1028

100μg/vial

315美元

单克隆

小鼠

未共轭

90000000000

人类, 大鼠

免疫印迹, 免疫组化, 免疫细胞化学

抗c Myc抗体(单克隆, 9E10)

315美元

100μg/vial

单克隆

90000000000

小鼠

人类

Monkey, Rabbit

免疫组化, 免疫细胞化学, 免疫印迹

Immunohistochemistry (Paraffin-embedded Section), 8µg/ml, Human, By Heat. Immunocytochemistry, 1µg/ml, Human Western blot, 4µg/ml, Human.

Other applications have not been tested. Optimal dilutions should be determined by end users.

Boster Bio Anti-c-Myc Antibody (Monoclonal, 9E10) catalog # MA1028. Tested in IHC, ICC, WB applications. This antibody reacts with Human.

Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Myc

P09416

合成多肽对应于氨基酸残基408-439人的p62c Myc蛋白

冻干

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

腹水

No cross reactivity with other proteins

小鼠IgG1

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Myc原癌基因蛋白

Myc原癌基因蛋白;原癌基因c Myc;转录因子p64;Myc;

Myc原癌基因蛋白

48898分子量

Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'- CAC[GA]TG-3'. Activates the transcription of growth-related genes.

Nucleus, nucleoplasm. Nucleus, nucleolus.

Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P) and ICC.

Contains 1 bHLH (basic helix-loop-helix) domain.

C-Myc is an oncogene that functions both in the stimulation of cell proliferation and in apoptosis. c-Myc elicits its oncogenic activity by causing immortalization, and to a lesser extent the transformation of cells, in addition to several other mechanisms. The c-MYC proto-oncogene encodes a transcription factor that is critical for cell growth and proliferation. It is one of the genes frequently altered in cancer cells in which it exhibits constitutive activity. Downregulation of c-Myc is critical for 2-Methoxyestradiol (2ME2)-induced oxidative stress and apoptosis in AML cells. And its up-regulation is important for promoting lymphocyte cell division, and demonstrating that GFP-c-Myc expression is a marker of proliferating lymphocytes in vivo.

Cancer, Cell Cycle, Cell Differentiation, Domain Families, Epigenetics and Nuclear Signaling, Hlh / Leucine Zipper, Nuclear, Oncoproteins, Oncoproteins/Suppressors, Signaling Pathways, Stem Cells, Tgf Beta, Transcription, Transcription Factors, Tumor Biomarkers