抗体

抗钙粘蛋白P CDH3抗体(单克隆, CH-19)

MA1079

100μg/vial

315美元

单克隆

小鼠

未共轭

CH-19

人类, 小鼠, 大鼠, 鸡

免疫印迹, 免疫组化

抗钙粘蛋白P CDH3抗体(单克隆, CH-19)

315美元

100μg/vial

单克隆

CH-19

小鼠

鸡, 人类, 小鼠, 兔, 大鼠, 蛇

免疫组化, 免疫印迹

Immunohistochemistry (Paraffin-embedded Section), 2-4µg/ml, Human, mouse, rat, rabbit, chicken, snake., By Heat. Western blot, 1-2µg/ml, Human, mouse, rat, rabbit, chicken, snake.

Other applications have not been tested. Optimal dilutions should be determined by end users.

Boster Bio Anti-P-Cadherin-3 CDH3-Antibody (Monoclonal, CH-19) catalog # MA1079. Tested in IHC, WB applications. This antibody reacts with Chicken, Human, Mouse, Rabbit, Rat, Snake.

Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

CDH1;CDH2;CDH3

F1LMI3

Synthetic peptide corresponding to the C-terminal amino acids of chicken N-Cadherin with an extra N-terminal lysine residue (24 amino acids) coupled to KLH.

冻干

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

腹水

No cross reactivity with other proteins

小鼠IgG1

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

cadherin 1, type 1, E-cadherin(epithelial); cadherin 2, type 1, N-cadherin(neuronal); cadherin 3, type 1, P-cadherin(placental)

Cadherin 3, type 1, P-cadherin (Placental) ; Protein Cdh3 ; Cdh3 ; rCG_51631 ;

钙粘蛋白1;钙粘蛋白2;钙粘蛋白3

90415分子量

Cadherins are calcium-dependent cell adhesion proteins.

CDH1: Cell junction. Cell membrane; Single-passtype I membrane protein. Endosome. Golgi apparatus, trans-Golginetwork. Note: Colocalizes with DLGAP5 at sites of cell-cellcontact in intestinal epithelial cells. Anchored to actinmicrofilaments through association with alpha-, beta- and gamma-catenin. Sequential proteolysis induced by apoptosis or calciuminflux, results in translocation from sites of cell-cell contactto the cytoplasm. Colocalizes with RAB11A endosomes during itstransport from the Golgi apparatus to the plasma membrane. Cdh1: Cell junction. Cell membrane; Single-passtype I membrane protein. Endosome Golgi apparatus,trans-Golgi network Note: Colocalizes with DLGAP5 atsites of cell-cell contact in intestinal epithelial cells.Anchored to actin microfilaments through association with alpha-,beta- and gamma-catenin. Sequential proteolysis induced byapoptosis or calcium influx, results in translocation from sitesof cell-cell contact to the cytoplasm. Colocalizes with RAB11Aendosomes during its transport from the Golgi apparatus to theplasma membrane (By similarity). Cdh1: Cell junction. Cell membrane; Single-passtype I membrane protein. Endosome Golgi apparatus,trans-Golgi network Note: Colocalizes with DLGAP5 atsites of cell-cell contact in intestinal epithelial cells.Anchored to actin microfilaments through association with alpha-,beta- and gamma-catenin. Sequential proteolysis induced byapoptosis or calcium influx, results in translocation from sitesof cell-cell contact to the cytoplasm. Colocalizes with RAB11Aendosomes during its transport from the Golgi apparatus to theplasma membrane (By similarity). CDH2: Cell membrane; Single-pass type I membraneprotein. Cdh2: Cell membrane; Single-pass type I membraneprotein. Cdh2: Cell membrane CDH3: Cell membrane; Single-pass type I membraneprotein. Cdh3: Cell membrane; Single-pass type I membraneprotein.

CDH1: Non-neural epithelial tissues.

Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P).

含5钙粘蛋白区域

Cadherins are calcium-dependent cell-cell adhesion molecules that mediate cell-cell binding in a homophilic manner. They play an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. Cadherin expression is regulated spatially as well as temporally. Cadherins are though to play an important role in development and maintenance of tissues through selective cell-cell adhesion activity and may be involved also in the invasion and metastasis of malignant tumors. Cadherin regulates dendritic spine morphogenesis. A cadherin gene cluster is mapped to a region of chromosome 5 subject to frequent allelic loss in carcinoma.

Cadherins, Cell Adhesion, Cytoskeleton / Ecm, Neuroscience, Sensory System, Signal Transduction, Visual System