产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
抗体
产品名称 :
Anti-Paxillin Pxn Antibody (Monoclonal, PXC-10)
目录 :
MA1080
规格 :
100μg/vial
价格 :
315美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
PXC-10
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫印迹, 免疫细胞化学
图像
图像 1 :
武汉博士德生物工程有限公司 MA1080 图像 1
Anti-Paxillin antibody (monoclonal), MA1080, Western blotting. Lane 1: 293T Cell Lysate. Lane 2: HELA Cell Lysate. Lane 3: MCF-7 Cell Lysate. Lane 4: MM231 Cell Lysate. Lane 5: JURKAT Cell Lysate.
产品信息
SKU号 :
MA1080
产品名称 :
Anti-Paxillin Pxn Antibody (Monoclonal, PXC-10)
价格 :
315美元
规格 :
100μg/vial
克隆性 :
单克隆
克隆编号 :
PXC-10
宿主 :
小鼠
反应物种 :
鸡, 人类, 小鼠, 大鼠
前体活性 :
狗, 马, 兔
应用(s) :
免疫细胞化学, 免疫印迹
应用细节 :
免疫细胞化学, 1µg/毫升, 人类, 小鼠, 大鼠, 鸡免疫印迹, 1-2µg/毫升, 人类, 小鼠, 大鼠, 鸡
应用注释 :
Other applications have not been tested. Optimal dilutions should be determined by end users.
描述 :
Boster Bio Anti-Paxillin Pxn Antibody (Monoclonal, PXC-10) catalog # MA1080. Tested in ICC, WB applications. This antibody reacts with Chicken, Human, Mouse, Rat.
浓度 :
Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.
基因名称 :
PXN
UniProt数据库编号 :
Q66H76
免疫原 :
C-terminal part of recombinant chicken paxillin (amino acids 305-559).
形式 :
冻干
Contents :
Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
纯化 :
腹水
交叉活性 :
No cross reactivity with other proteins
抗体亚型 :
小鼠IgG1
储存 :
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
重组 :
Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
基因全称 :
Paxillin
同义词 :
Paxillin; Pxn;
蛋白名 :
Paxillin
分子量 :
64019分子量
Protein Function :
Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).
Subcellular Localization :
Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Cytoplasm, cell cortex. Colocalizes with integrins at the cell periphery. Colocalizes with PXN to membrane ruffles and the leading edge of migrating cells (By similarity).
Recommended Detection Systems :
Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for ICC.
Sequence Similarities :
Belongs to the paxillin family.
背景 :
The paxillin gene can be alternatively spliced to include 1 of 2 alternative exons, generating beta and gamma isoforms. Paxillin is a 68-kDa focal adhesion protein that is phosphorylated on tyrosine residues in fibroblasts in response to transformation by v-src, treatment with platelet-derived growth factor, or cross-linking of integrins. The 68-kD protein (paxillin) is a cytoskeletal component that localizes to the focal adhesions at the ends of actin stress fibers in chicken embryo fibroblasts. It is also present in the focal adhesions of Madin-Darby bovine kidney (MDBK) epithelial cells but is absent, like talin, from the cell-cell adherens junctions of these cells.
研究种类 :
Adapters, Cancer, Cytoplasmic, Cytoskeleton / Ecm, Extracellular Matrix, Signal Transduction, Structures
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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