抗体

抗S-100(乙亚单位)S100钙结合蛋白B抗体(单克隆, SH-B1)

MA1088

100μg/vial

315美元

单克隆

小鼠

未共轭

SH-B1

人类, 大鼠

抗S-100(乙亚单位)S100钙结合蛋白B抗体(单克隆, SH-B1)

315美元

100μg/vial

单克隆

SH-B1

小鼠

人类, 兔, 大鼠

Horse, Monkey, Rabbit

免疫组化

Immunohistochemistry (Paraffin-embedded Section), 1-2µg/ml, Human, rabbit, rat, By Heat.

Other applications have not been tested. Optimal dilutions should be determined by end users.

Boster Bio Anti-S-100 (Beta-subunit) S100b Antibody (Monoclonal, SH-B1) catalog # MA1088. Tested in IHC applications. This antibody reacts with Human, Rabbit, Rat.

Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

S100B

P04631

牛大脑S-100b

冻干

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

腹水

No cross reactivity with other proteins

小鼠IgG1

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

蛋白S100-B

蛋白S100-B;S-100蛋白乙链;S-100蛋白亚基乙;S100钙结合蛋白B;S100钙结合蛋白B;

蛋白S100-B

10744分子量

Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

Cytoplasm. Nucleus.

Although predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues.

Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P).

Belongs to the S-100 family.

S100 protein is a 21,000-Da component first isolated from brain by Moore (1965). Immunocytochemical studies demonstrated that S100 protein is produced by a wide variety of normal and neoplastic cells of mesodermal, neuroectodermal, and epithelial origin (Herrera et al., 1988). The S100 molecule is a dimer; thus there are 3 forms of S100: alpha-alpha, known as S-100a (0); alpha-beta, known as S-100a; and beta-beta, known as S-100b. S100 genes are clustered on human chromosome 1q21. S-100 protein expression by primary and metastatic adenocarcinomas.

Cell Biology, Cell Cycle, Cell Differentiation, Epigenetics and Nuclear Signaling, Neural Stem Cells, Stem Cells