产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
抗体
产品名称 :
Anti-Tau Antibody (Monoclonal, TAU-2)
目录 :
MA1093
规格 :
100 ug/vial
价格 :
280美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
克隆名称 :
Tau-2
反应物种 :
人类, 大鼠,
应用 :
免疫印迹, 免疫组化
图像
图像 1 :
武汉博士德生物工程有限公司 MA1093 图像 1
Anti-Tau antibody (monoclonal), MA1093, Western blotting. Lane 1: Rat Brain Tissue Lysate. Lane 2: Rat Brain Tissue Lysate. Lane 3: Mouse Brain Tissue Lysate. Lane 4: Mouse Brain Tissue Lysate.
产品信息
SKU号 :
MA1093
状态 :
Enabled
名称 :
Anti-Tau Antibody (Monoclonal, TAU-2)
目录名称 :
免疫组化免疫细胞化学IF抗体
基因名称 :
MAPT
价格 :
280美元
price various sizes :
30ug sample size / $99 100ug / $280 100ug+Free HRP Secondary BA1050 / $280 100ug+Free Biotin Secondary BA1001 / $280
克隆性 :
单克隆
克隆编号 :
TAU-2
浓度 :
Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
共轭标签 :
No
contents :
Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
描述 :
Monoclonal clone# G2 antibody for Tau/MAPT detection. Host: Mouse.Size: 100ug/vial. Tested applications: IHC-P. Reactive species: Bovine. Tau/MAPT information: Molecular Weight: 78564 MW; Subcellular Localization: Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components; Tissue Specificity: Expressed in neurons. The larger forms (isoform tau-A and isoform tau-B) are preferentially expressed in the peripheral nervous system while the other are expressed in the central nervous system. Low amounts of the larger forms are also found in limited areas of the CNS.
short description :
Mouse IgG monoclonal antibody for Tau, microtubule-associated protein tau (MAPT) detection. Tested with WB, IHC-P in Human;bovine. No cross reactivity with other proteins.
规格 :
100 ug/vial
sample size available :
30ug for $99, contact us for details
UniProt数据库编号 :
P19332
宿主 :
小鼠
免疫原 :
牛微管相关蛋白(地图)
形式 :
冻干
纯化 :
腹水
储存 :
At -20 C for one year. After reconstitution, at 4 C for one month. It can also be aliquotted and stored frozen at -20 C for a longer time.Avoid repeated freezing and thawing.
交叉活性 :
No cross reactivity with other proteins
抗体亚型 :
小鼠IgG1
重组 :
Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
应用细节 :
Immunohistochemistry(Paraffin-embedded Section), 1-2ug/ml, Human, bovine, By Heat . Western blot, 0.5-1ug/ml, Human, bovine.
应用 :
免疫组化, 免疫印迹
反应物种 :
牛, 人类
图像标记 :
Anti-Tau antibody (monoclonal), MA1093, Western blotting. Lane 1: Rat Brain Tissue Lysate. Lane 2: Rat Brain Tissue Lysate. Lane 3: Mouse Brain Tissue Lysate. Lane 4: Mouse Brain Tissue Lysate.
背景 :
The microtubule-associated proteins(MAPs) coassemble with tubulin into microtubules in vitro. Microtubule-associated protein tau appears to be enriched in axons. Tau are composed of 352 to 441 amino acids. The isoforms differ from each other by the presence or absence of 29-amino acid or 58-amino acid inserts located in the N terminus and a 31-amino repeat located in the C terminus. tau is important in establishing and maintaining neuronal morphology and is a major component of the neurofibrillary tangles(NFTs) characteristic of Alzheimer's brain. Microtubule-associated protein tau(MTBT1) is mapped to chromosome 17q21.
competitor equivalent skus :
sc 101556 sc 101555 sc 28976 sc 19546 sc 19547
研究种类 :
Neurodegenerative Disease, Neurology Process, Neuron Marker, Neuroscience, Signal Transduction
同义词 :
Microtubule-associated protein tau;Neurofibrillary tangle protein;Paired helical filament-tau;PHF-tau;Mapt;Mtapt, Tau;
基因全称 :
Microtubule-associated protein tau
分子量 :
78564分子量
protein function :
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
subcellular localization :
Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components.
组织特异性 :
Expressed in neurons. The larger forms (isoform tau-A and isoform tau-B) are preferentially expressed in the peripheral nervous system while the other are expressed in the central nervous system. Low amounts of the larger forms are also found in limited areas of the CNS.
蛋白名 :
Microtubule-associated protein tau
recommended detection systems :
Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P).
sequence similarities :
Contains 4 Tau/MAP repeats.
更新 :
1/28/19 19:39
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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