产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
抗体
产品名称 :
Anti-Beta-Actin Actb Antibody (Monoclonal, AC-15)
目录 :
MA1115
规格 :
100μg/vial
价格 :
315美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
AC-15
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化
文章摘录数: 34
参考文献
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Qi B, Chen H, Shang D, Dong Y, Zhang G, Yu L. Effects of hypoxia-inducible factor-1α and matrix metalloproteinase-9 on alveolar-capillary barrier disruption and lung edema in rat models of severe acute pancreatitis-associated lung injury. Exp Ther Med. 2014;8:899-906 pubmed
Shi J, Li J, Hu R, Shi Y, Su X, Guo X, et al. Tristetraprolin is involved in the glucocorticoid-mediated interleukin 8 repression. Int Immunopharmacol. 2014;22:480-5 pubmed 出版商
Wang T, Zhou Y, Chen X, Zhu A. Putative role of ischemic postconditioning in a rat model of limb ischemia and reperfusion: involvement of hypoxia-inducible factor-1α expression. Braz J Med Biol Res. 2014;47:738-45 pubmed
Mana L, Wang S, Zhu H, Xing Y, Lou L, Wu A, et al. Qingkailing Suppresses the Activation of BV2 Microglial Cells by Inhibiting Hypoxia/Reoxygenation-Induced Inflammatory Responses. Evid Based Complement Alternat Med. 2014;2014:696218 pubmed 出版商
Shen T, Liu K, Miao D, Cao R, Chen P. Effective inhibition of Japanese encephalitis virus replication by shRNAs targeting various viral genes in vitro and in vivo. Virology. 2014;454-455:48-59 pubmed 出版商
Cheng C, Huang C, Ma T, Bian E, He Y, Zhang L, et al. SOCS1 hypermethylation mediated by DNMT1 is associated with lipopolysaccharide-induced inflammatory cytokines in macrophages. Toxicol Lett. 2014;225:488-97 pubmed 出版商
Zhao M, Chen Y, Dong X, Zhou J, Chen X, Wang H, et al. Folic acid protects against lipopolysaccharide-induced preterm delivery and intrauterine growth restriction through its anti-inflammatory effect in mice. PLoS ONE. 2013;8:e82713 pubmed 出版商
Zhao M, Chen Y, Chen X, Dong X, Zhou J, Wang H, et al. Folic acid supplementation during pregnancy protects against lipopolysaccharide-induced neural tube defects in mice. Toxicol Lett. 2014;224:201-8 pubmed 出版商
Tang H, Deng M, Tang Y, Xie X, Guo J, Kong Y, et al. miR-200b and miR-200c as prognostic factors and mediators of gastric cancer cell progression. Clin Cancer Res. 2013;19:5602-12 pubmed 出版商
Gao K, Li X, Zhang L, Bai L, Dong W, Gao K, et al. Transgenic expression of IL-33 activates CD8(+) T cells and NK cells and inhibits tumor growth and metastasis in mice. Cancer Lett. 2013;335:463-71 pubmed 出版商
Wang Y, Tian F, Liu H, Zhang W, Li J, Xiao B, et al. Macrophage migration inhibitory factor is necessary for the lipo-oligosaccharide-induced response by modulation of Toll-like receptor 4 in monocytes from GBS patients. J Neuroimmunol. 2013;257:67-75 pubmed 出版商
Zhou H, Chen X, Zhang W, Zhu L, Cheng L. HIF-1? inhibition reduces nasal inflammation in a murine allergic rhinitis model. PLoS ONE. 2012;7:e48618 pubmed 出版商
Ni Y, Jiang T, Cheng Q, Gu Z, Zhu Y, Zhang Z, et al. Protective effect of magnolol on lipopolysaccharide-induced acute lung injury in mice. Inflammation. 2012;35:1860-6 pubmed 出版商
Tang S, Wang X, Hong H, Long Y, Li Y, Xiang G, et al. Leukotriene D4 induces cognitive impairment through enhancement of CysLT? R-mediated amyloid-? generation in mice. Neuropharmacology. 2013;65:182-92 pubmed 出版商
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Chen Y, Zhao M, Chen X, Zhang Y, Wang H, Huang Y, et al. Zinc supplementation during pregnancy protects against lipopolysaccharide-induced fetal growth restriction and demise through its anti-inflammatory effect. J Immunol. 2012;189:454-63 pubmed 出版商
Kong J, Kong J, Pan B, Ke S, Dong S, Li X, et al. Insufficient radiofrequency ablation promotes angiogenesis of residual hepatocellular carcinoma via HIF-1?/VEGFA. PLoS ONE. 2012;7:e37266 pubmed 出版商
Wang S, Wu X, Chen Y, Zhang J, Ding J, Zhou Y, et al. Prognostic and predictive role of JWA and XRCC1 expressions in gastric cancer. Clin Cancer Res. 2012;18:2987-96 pubmed 出版商
Li J, Zha X, Wang R, Li X, Xu B, Xu Y, et al. Regulation of CD44 expression by tumor necrosis factor-? and its potential role in breast cancer cell migration. Biomed Pharmacother. 2012;66:144-50 pubmed 出版商
Su Y, Liu W, Ma L, Liu X, Liu Z, Zhu B. Scutellarin inhibits translocation of protein kinase C in diabetic thoracic aorta of the rat. Clin Exp Pharmacol Physiol. 2012;39:136-40 pubmed 出版商
Zhang L, Wu S, Ruan Y, Hong L, Xing X, Lai W. Testosterone therapy delays cardiomyocyte aging via an androgen receptor-independent pathway. Braz J Med Biol Res. 2011;44:1118-24 pubmed
Meng L, Yu B. Oxygen- and glucose-deprived culture promotes cell proliferation and invasion of vascular smooth muscle cells. Int J Mol Med. 2011;28:777-83 pubmed 出版商
Lang Q, Liu Q, Xu N, Qian K, Qi J, Sun Y, et al. The antifibrotic effects of TGF-?1 siRNA on hepatic fibrosis in rats. Biochem Biophys Res Commun. 2011;409:448-53 pubmed 出版商
Ni Y, Kuai J, Lu Z, Yang G, Fu H, Wang J, et al. Glycyrrhizin treatment is associated with attenuation of lipopolysaccharide-induced acute lung injury by inhibiting cyclooxygenase-2 and inducible nitric oxide synthase expression. J Surg Res. 2011;165:e29-35 pubmed 出版商
Ni Y, Wang J, Yan X, Tian F, Zhao J, Wang Y, et al. Histone deacetylase inhibitor, butyrate, attenuates lipopolysaccharide-induced acute lung injury in mice. Respir Res. 2010;11:33 pubmed 出版商
Su H, Yang J, Xu T, Huang J, Xu L, Yuan Y, et al. MicroRNA-101, down-regulated in hepatocellular carcinoma, promotes apoptosis and suppresses tumorigenicity. Cancer Res. 2009;69:1135-42 pubmed 出版商
Chang Y, Wei W, Zhang L, Xu H. Effects and mechanisms of total glucosides of paeony on synoviocytes activities in rat collagen-induced arthritis. J Ethnopharmacol. 2009;121:43-8 pubmed 出版商
Bi Y, Sun W, Chen X, Li M, Liang H, Cai M, et al. Effect of early insulin therapy on nuclear factor kappaB and cytokine gene expressions in the liver and skeletal muscle of high-fat diet, streptozotocin-treated diabetic rats. Acta Diabetol. 2008;45:167-78 pubmed 出版商
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图像
图像 1 :
武汉博士德生物工程有限公司 MA1115 图像 1
Anti-beta-Actin antibody (monoclonal), MA1115, Western blotting. Lane 1: Rat Ovary Tissue Lysate. Lane 2: Rat Testis Tissue Lysate. Lane 3: Rat Cardiac Muscle Tissue Lysate. Lane 4: Rat Brain Tissue Lysate. Lane 5: A453 Cell Lysate. Lane 6: HE
图像 2 :
武汉博士德生物工程有限公司 MA1115 图像 2
Anti-beta-Actin antibody (monoclonal), MA1115, Western blotting. Lane 1: Rat Liver Tissue Lysate. Lane 2: Rat Spleen Tissue Lysate. Lane 3: Rat Brain Tissue Lysate. Lane 4: Rat Kidney Tissue Lysate. Lane 5: HELA Cell Lysate. Lane 6: SMMC Cell
图像 3 :
武汉博士德生物工程有限公司 MA1115 图像 3
Anti-beta-Actin antibody (monoclonal), MA1115, IHC(P). IHC(P): Mouse Intestine Tissue
产品信息
SKU号 :
MA1115
产品名称 :
Anti-Beta-Actin Actb Antibody (Monoclonal, AC-15)
价格 :
315美元
规格 :
100μg/vial
克隆性 :
单克隆
克隆编号 :
AC-15
宿主 :
小鼠
反应物种 :
Chicken, Human, Monkey, Mouse, Pig, Rabbit, Rat
前体活性 :
Bovine, Chicken, Canine, Hamster, Horse, Monkey, Rabbit, Zebrafish
应用(s) :
免疫组化, 免疫印迹
应用细节 :
Western blot, 0.05-0.1µg/ml, Human, mouse, rat, pig, monkey, rabbit, chicken. Immunohistochemistry (Paraffin-embedded Section), 0.5-1µg/ml, Human, mouse, rat, By Heat.
应用注释 :
Other applications have not been tested. Optimal dilutions should be determined by end users.
描述 :
Boster Bio Anti-Beta-Actin Actb Antibody (Monoclonal, AC-15) catalog # MA1115. Tested in IHC, WB applications. This antibody reacts with Chicken, Human, Monkey, Mouse, Pig, Rabbit, Rat.
浓度 :
Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.
基因名称 :
ACTB
UniProt数据库编号 :
P60711
免疫原 :
slightly modified beta-cytoplasmic actin N-terminal peptide, Ac-Asp-Asp-Asp-Ile-Ala-Ala-Leu-Val-Ile-Asp-Asn-Gly-Ser-Gly-Lys, conjugated to KLH.
形式 :
冻干
Contents :
Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
纯化 :
腹水
交叉活性 :
No cross reactivity with other proteins
抗体亚型 :
小鼠IgG1
储存 :
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
重组 :
Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
基因全称 :
Actin, cytoplasmic 1
同义词 :
Actin, cytoplasmic 1; Beta-actin; Actin, cytoplasmic 1, N-terminally processed; Actb;
蛋白名 :
Actin, cytoplasmic 1
分子量 :
41737分子量
Protein Function :
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
Subcellular Localization :
Cytoplasm, cytoskeleton. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Recommended Detection Systems :
Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P).
Sequence Similarities :
Belongs to the actin family.
背景 :
The primary site of action of cytochalasin B on cell motility processes is beta-actin. Habets et al. (1992) generated hybrids that harbor only specific regions of human chromosome 7 and assigned the ACTB locus to 7p15-p12. ACTB and the other assigned beta-actin-related sequences are dispersed over at least four different chromosomes including one locus assigned to the X chromosome. A mutation of beta-actin that alters depolymerization dynamics is associated with autosomal dominant developmental malformations, deafness, and dystonia.
研究种类 :
Actin, Actin Etc, Cytoskeleton, Cytoskeleton / Ecm, Microfilaments, Signal Transduction
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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