Anti-Phospho-Tau (Ser416) Antibody | 武汉博士德生物工程有限公司 P00097 产品信息

产品简要

公司名称 :

武汉博士德生物工程有限公司

产品类型 :

其他

产品名称 :

Anti-Phospho-Tau (Ser416) Antibody

P00097

规格 :

100微升

价格 :

300美元

更多信息或购买 :

武汉博士德生物工程有限公司产品网页

产品信息

SKU号 :

P00097

状态 :

Enabled

名称 :

Anti-Phospho-Tau (Ser416) Antibody

目录名称 :

一抗, 多克隆抗体, 免疫组化免疫细胞化学IF抗体

基因名称 :

MAPT

价格 :

300美元

price various sizes :

100ul / $300 100ul+Free HRP Secondary BA1054 / $300 100ul+Free Biotin Secondary BA1003 / $300

克隆性 :

多克隆

浓度 :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

共轭标签 :

contents :

100 ul in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol.

描述 :

Polyconal antibody for Tau/MAPT detection. Host: Rabbit.Size: 100ul. Tested applications: IHC. Reactive species: Mouse. Tau/MAPT information: Molecular Weight: 78928 MW; Subcellular Localization: Cytoplasm, cytosol . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cytoskeleton . Cell projection, axon . Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components; Tissue Specificity: Expressed in neurons. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.

short description :

Phospho-specific Rabbit Anti-Tau (Ser 416 ) Antibody tested for IHC, WB in mouse, rat.

规格 :

100微升

UniProt数据库编号 :

P10636

宿主 :

兔

免疫原 :

The antigen is a phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser416 of rat tau.

形式 :

Liquid

储存 :

At -20 C for one year. After reconstitution, at 4 C for one month. It can also be aliquotted and stored frozen at -20 C for a longer time.Avoid repeated freezing and thawing.

应用细节 :

免疫印迹, 1:1, 000

应用 :

免疫印迹

反应物种 :

小鼠, 大鼠

前体活性 :

牛, 狗, 人类

图像标记 :

Western blot of rat brain homogenate showing specific immunolabeling of the ~59 kDa, ~65 kDa,~ 68 kDa Tau isoforms phosphorylated at Ser 416 in the first lane (-). Phosphospecificity is shown in the second lane (+) where immunolabeling is blocked by preadsorption with the phosphopeptide used as antigen, but not by the corresponding non-phosphopeptide (not shown).

研究种类 :

Alzheimer'S Disease, Cell Type Marker, Cytoskeleton, Cytoskeleton / Ecm, Microtubules, Neurodegenerative Disease, Neurology Process, Neuron Marker, Neuroscience, Signal Transduction

同义词 :

Microtubule-associated protein tau;Neurofibrillary tangle protein;Paired helical filament-tau;PHF-tau;MAPT;MAPTL, MTBT1, TAU;

基因全称 :

Microtubule-associated protein tau

分子量 :

78928分子量

protein function :

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

subcellular localization :

Cytoplasm, cytosol . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cytoskeleton . Cell projection, axon . Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components.

组织特异性 :

Expressed in neurons. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.

蛋白名 :

Microtubule-associated protein tau

更新 :

2/6/19 22:57

更多信息或购买 :

武汉博士德生物工程有限公司产品网页

公司信息