产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
抗体
产品名称 :
抗CCR5抗体
目录 :
PA1016
规格 :
100 ug/vial
价格 :
240美元
克隆性 :
多克隆
宿主 :
共轭标签 :
nonconjugated
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹
图像
图像 1 :
武汉博士德生物工程有限公司 PA1016 图像 1
Anti-CCR5 antibody, PA1016, Western blotting. Lane 1: JURKAT Cell Lysate. Lane 2: COLO320 Cell Lysate.
图像 2 :
武汉博士德生物工程有限公司 PA1016 图像 2
Anti-CCR5 antibody, PA1016, Western blotting. All lanes: Anti CCR5 (PA1016) at 0.5ug/ml. WB: Mouse Liver Tissue Lysate at 50ug. Predicted bind size: 40KD. Observed bind size: 40KD
产品信息
SKU号 :
PA1016
状态 :
Enabled
名称 :
抗CCR5抗体
目录名称 :
一抗, 多克隆抗体
基因名称 :
CCR5
价格 :
240美元
price various sizes :
30ug sample size / $59 100ug / $240 100ug+Free HRP Secondary BA1054 / $240 100ug+Free Biotin Secondary BA1003 / $240
克隆性 :
多克隆
浓度 :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
共轭标签 :
No
contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
描述 :
Polyclonal antibody for CCR5 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: IHC-P. Reactive species: Human. CCR5 information: Molecular Weight: 40524 MW; Subcellular Localization: Cell membrane ; Multi-pass membrane protein ; Tissue Specificity: Highly expressed in spleen, thymus, in the myeloid cell line THP-1, in the promyeloblastic cell line KG-1a and on CD4+ and CD8+ T-cells. Medium levels in peripheral blood leukocytes and in small intestine. Low levels in ovary and lung.
short description :
Rabbit IgG polyclonal antibody for C-C chemokine receptor type 5(CCR5) detection. Tested with WB in Human;Mouse;Rat.
规格 :
100 ug/vial
sample size available :
30ug for $99, contact us for details
UniProt数据库编号 :
P51681
宿主 :
免疫原 :
A synthetic peptide corresponding to a sequence at the N-terminus of human CCR5(19-34aa PCQKINVKQIAARLLP), different from the related rat sequence by two amino acids.
形式 :
冻干
纯化 :
免疫原亲和纯化
储存 :
At -20 C for one year. After reconstitution, at 4 C for one month. It can also be aliquotted and stored frozen at -20 C for a longer time.Avoid repeated freezing and thawing.
交叉活性 :
No cross reactivity with other proteins
重组 :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
应用细节 :
免疫印迹, 0.1 0.5微克/毫升, 人类, 小鼠, 大鼠
应用 :
免疫印迹
反应物种 :
人类, 小鼠, 大鼠
图像标记 :
Anti-CCR5 antibody, PA1016, Western blotting. Lane 1: JURKAT Cell Lysate. Lane 2: COLO320 Cell Lysate. Anti-CCR5 antibody, PA1016, Western blotting. All lanes: Anti CCR5 (PA1016) at 0.5ug/ml. WB: Mouse Liver Tissue Lysate at 50ug. Predicted bind size: 40KD. Observed bind size: 40KD
背景 :
Human CC chemokine receptor 5(CCR5), which is 17.5 kb from the CMKBR2 gene, encodes a 352-amino acid protein with a calculated molecular mass of 40,600 Da. It is organized into four exons and two introns. Human CCR5 is a co-receptor for macrophage-tropic strains of human immunodeficiency virus(HIV)-1 and is expressed by bone-marrow-derived cells. CCR5 is expressed on neurons, astrocytes, and microglia in the central nervous system, and on epithelium, endothelium, vascular smooth muscle and fibroblasts in other tissues. Functionally, CCR5 mediates the activation of cells by the chemokines macrophage inflammatory protein-1alpha, macrophage inflammatory protein-1beta, and RANTES, and serves as a fusion cofactor for macrophage-tropic strains of human immunodeficiency virus type 1.
competitor equivalent skus :
sc 21932 sc 21929
研究种类 :
Alzheimer'S Disease, Antiviral Signaling, Atherosclerosis, Cancer, Cardiovascular, Chemokines, G Protein Signaling, Host Virus Interaction, Immune System Diseases, Immunology, Innate Immunity, Interspecies Interaction, Macrophage / Inflamm., Microbiology, Neurodegenerative Disease, Neurology Process, Neuroscience, Signal Transduction, Signaling Pathway, Vascular Inflammation
同义词 :
C-C chemokine receptor type 5;C-C CKR-5;CC-CKR-5;CCR-5;CCR5;CHEMR13;HIV-1 fusion coreceptor;CD195;CCR5;CMKBR5;
基因全称 :
C-趋化因子C受体类型5
分子量 :
40524分子量
protein function :
Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.
subcellular localization :
Cell membrane ; Multi-pass membrane protein .
组织特异性 :
Highly expressed in spleen, thymus, in the myeloid cell line THP-1, in the promyeloblastic cell line KG-1a and on CD4+ and CD8+ T-cells. Medium levels in peripheral blood leukocytes and in small intestine. Low levels in ovary and lung.
蛋白名 :
C-趋化因子C受体类型5(C-C CKR-5/CC-CKR-5/CCR-5/CCR5)
recommended detection systems :
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.
sequence similarities :
Belongs to the G-protein coupled receptor 1 family.
更新 :
4/1/19 8:22
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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