抗体

抗CD40抗体

PA1019-1

100μg/vial

315美元

多克隆

domestic rabbit

未共轭

免疫印迹, 流式细胞仪

抗CD40抗体

315美元

100μg/vial

多克隆

兔

人类

流式细胞仪, 免疫印迹

免疫印迹, 0.1 0.5µg/毫升, 人类。 流式细胞仪, 1-3微克/1x10^6细胞, 人类

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Boster Bio Anti-CD40 Antibody catalog # PA1019-1. Tested in Flow Cytometry, WB applications. This antibody reacts with Human.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

CD40

P25942

A synthetic peptide corresponding to a sequence at the N-terminus of human CD40 (20-37aa, PEPPTACREKQYLINSQC).

冻干

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

免疫原亲和纯化

No cross reactivity with other proteins

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Tumor necrosis factor receptor superfamily member 5

Tumor necrosis factor receptor superfamily member 5; B-cell surface antigen CD40; Bp50; CD40L receptor; CDw40; CD40; CD40; TNFRSF5;

Tumor necrosis factor receptor superfamily member 5

30619分子量

Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.

Isoform I: Cell membrane; Single-pass type I membrane protein.

B-cells and in primary carcinomas.

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.

Contains 4 TNFR-Cys repeats.

CD40 is a cell surface receptor that is expressed on the surface of all mature B cells and also expressed on monocytes, dendritic cells, and thymic epithelium. CD40 is a member of the tumor necrosis factor (TNF) receptor superfamily and is the receptor for CD40 ligand. CD40 ligand (CD40L, CD154, gp39, and TRAM) belongs to the TNF gene family and is expressed more widely than CD40 predominantly on activated CD4+ T cells. Activation of CD40 has also been shown to inhibit the growth of certain B cell lymphomas and to induce the death of transformed cells of mesenchymal or epithelial origin.

Adaptive Immunity, Atherosclerosis, B Cells, Cardiovascular, Hematopoietic Progenitors, Immunology, Lymphoid, Myeloid, Stem Cells, Vascular Inflammation