产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
抗体
产品名称 :
抗核纤层蛋白B1/LMNB1抗体
目录 :
PA1048
规格 :
100μg/vial
价格 :
315美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学
图像
图像 1 :
武汉博士德生物工程有限公司 PA1048 图像 1
Anti-Lamin B1 antibody, PA1048, Western blotting. Lane 1: MCF-7 Cell Lysate. Lane 2: HELA Cell Lysate.
图像 2 :
武汉博士德生物工程有限公司 PA1048 图像 2
Anti-Lamin B1 antibody, PA1048, IHC(P). IHC(P): Human Mammary Cancer Tissue
图像 3 :
武汉博士德生物工程有限公司 PA1048 图像 3
Anti-Lamin B1 antibody, PA1048, IHC(F). IHC(F): Rat Intestine Tissue
产品信息
SKU号 :
PA1048
产品名称 :
抗核纤层蛋白B1/LMNB1抗体
价格 :
315美元
规格 :
100μg/vial
克隆性 :
多克隆
宿主 :
反应物种 :
人类, 小鼠, 大鼠
前体活性 :
仓鼠
应用(s) :
免疫组化, 免疫细胞化学, 免疫印迹
应用细节 :
Immunohistochemistry (Paraffin-embedded Section), 0.5-1µg/ml, Human, Rat, By Heat. Immunocytochemistry, 0.5-1µg/ml, Human, RatImmunohistochemistry (Frozen Section), 0.5-1µg/ml, Rat, Human Western blot, 0.1-0.5µg/ml, Human, Mouse, Rat.
应用注释 :
Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staning of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
描述 :
Boster Bio Anti-Lamin B1/LMNB1 Antibody catalog # PA1048. Tested in IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
浓度 :
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
基因名称 :
LMNB1
UniProt数据库编号 :
P20700
免疫原 :
A synthetic peptide corresponding to a sequence at the C-terminus of human Lamin B1 (570-586aa FHQQGTPRASNRSCAIM), different from the related rat sequence by one amino acid, and from the related mouse sequence by three amino acids.
形式 :
冻干
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
纯化 :
免疫原亲和纯化
交叉活性 :
No cross reactivity with other proteins
储存 :
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
重组 :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
基因全称 :
核纤层蛋白B1
同义词 :
核纤层蛋白B1;LMNB1;LMN2, LMNB;
蛋白名 :
核纤层蛋白B1
分子量 :
66408分子量
Protein Function :
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
Subcellular Localization :
Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side.
Recommended Detection Systems :
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P), IHC(F) and ICC.
Sequence Similarities :
Belongs to the intermediate filament family.
背景 :
Lamin-B1 is a protein that in humans is encoded by the LMNB1 gene. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are though to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.
研究种类 :
Apoptosis, Cancer, Cell Biology, Cell Death, Cytoskeleton, Cytoskeleton / Ecm, Intermediate Filaments, Nucleus, Signal Transduction, Subcellular Markers, Tags & Cell Markers
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
Premium Provider of Antibodies and ELISA Kits