抗体

抗OPCML抗体

PA1131

100μg/vial

315美元

多克隆

domestic rabbit

未共轭

人类, 小鼠, 大鼠

免疫印迹, 免疫组化

抗OPCML抗体

315美元

100μg/vial

多克隆

兔

大鼠, 小鼠, 人类

仓鼠

免疫组化, 免疫印迹

Immunohistochemistry (Paraffin-embedded Section), 0.5-1µg/ml, Human, Rat, Mouse, By Heat. Western blot, 0.1-0.5µg/ml, Human, Rat, Mouse.

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Boster Bio Anti-OPCML Antibody catalog # PA1131. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

OPCML

Q14982

A synthetic peptide corresponding to a sequence at the C-terminus of human OPCML (294-312aa YTCVATNKLGNTNASITLY), identical to the related rat and mouse sequences.

冻干

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

免疫原亲和纯化

No cross reactivity with other proteins

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Opioid-binding protein/cell adhesion molecule

Opioid-binding protein/cell adhesion molecule; OBCAM; OPCML; Opioid-binding cell adhesion molecule; IgLON family member 1; OPCML; IGLON1, OBCAM;

Opioid-binding protein/cell adhesion molecule(OBCAM/OPCML/Opioid-binding cell adhesion molecule)

38008分子量

Binds opioids in the presence of acidic lipids; probably involved in cell contact.

Cell membrane ; Lipid-anchor, GPI-anchor.

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

Belongs to the immunoglobulin superfamily. IgLON family.

Opioid-binding protein/cell adhesion molecule-like (OPCML), (also called opioid-binding cell adhesion molecule (OBCAM). OPCML is a member of the IgLON family of immunoglobulin (Ig) domain-containing glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecules, as an excellent candidate for the 11q25 ovarian cancer TSG in EOC. The OPCML gene comprises 7 exons, spans approximately 600 kb, and is transcribed from telomere to centromere . And due to the lack of transmembrane domains necessary for signal transduction, it is improbable that OBCAM acts independently as an opioid receptor; more likely, it plays an important accessory role in opioid receptor function.

Cancer, Cell Adhesion Proteins, Membrane Proteins, Neuroscience, Neurotransmission, Oncoproteins/Suppressors, Receptors / Channels, Tumor Suppressors