抗体

抗MRGX1/MRGPRX1抗体

PA1208

100μg/vial

315美元

多克隆

domestic rabbit

未共轭

免疫印迹, 免疫组化

抗MRGX1/MRGPRX1抗体

315美元

100μg/vial

多克隆

兔

大鼠

免疫组化, 免疫印迹

Immunohistochemistry (Paraffin-embedded Section), 0.5-1µg/ml, Rat, By Heat. Western blot, 0.1-0.5µg/ml, Rat.

Boster Bio Anti-MRGX1/MRGPRX1 Antibody catalog # PA1208. Tested in IHC, WB applications. This antibody reacts with Rat.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

MRGPRX1

Q8R4G1

A synthetic peptide corresponding to a sequence at the N-terminus of rat MRGX1 (14-28aa TLNKTGHPSCRPILT).

冻干

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

免疫原亲和纯化

No cross reactivity with other proteins

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Mas-related G-protein coupled receptor member X1

Mas-related G-protein coupled receptor member X1; Sensory neuron-specific G-protein coupled receptor 1; Mrgprx1; Mrgc, Mrgprc, Mrgprc11, Snsr, Snsr1;

Mas-related G-protein coupled receptor member X1

37074分子量

Orphan receptor activated by neuropeptides terminating in Arg-Phe or Arg-Phe-amide. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G (q) and G (11) proteins. May regulate the function of nociceptive neurons by modulation of pain perception (By similarity).

Cell membrane; Multi-pass membrane protein.

Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons. Associated preferentially with IB4 class of small-diameter somatosensory afferents (also known as nociceptors).

Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P).

Belongs to the G-protein coupled receptor 1 family. Mas subfamily.

MAS-related G-protein coupled receptor, member C, also known as MRGPRC or MRGPRX1, is a human gene. The Mas-related genes (Mrgs) comprise a family of >50 G protein-coupled receptors (GPCRs), many of which are expressed in specific subsets of nociceptive sensory neurons in mice. In contrast, humans contain a related but nonorthologous family of genes, called MrgXs or sensory neuron-specific receptors, of which many fewer appear to be expressed in sensory neurons.

G Protein Signaling, Signal Transduction, Signaling Pathway