抗体

抗胱蛋白C抗体

PA1369

100 ug/vial

200美元

多克隆

兔

nonconjugated

免疫印迹, 免疫细胞化学, 免疫组化-石蜡切片

抗胱蛋白C抗体

200美元

A synthetic peptide corresponding to a sequence at the C-terminus of human Cystatin C(45-63aa EEEGVRRALDFAVGEYNKA).

冻干

兔

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

免疫原亲和纯化

多克隆

Rabbit IgG polyclonal antibody for Cystatin-C(CST3) detection. Tested with WB, IHC-P, ICC in Human.

100 ug/vial

人类

免疫组化-P;免疫细胞化学;免疫印迹

Cystatin C or cystatin 3, a protein encoded by the CST3 gene, is mainly used as a biomarker of kidney function. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid, such as Alzheimer's disease. By human-rodent somatic cell hybridizations, Abrahamson et al.(1989) mapped the human CST3 to chromosome 20. Cystatin C was originally described as a constituent of normal cerebrospinal fluid(CSF) and of urine from patients with renal failure(Grubb and Lofberg, 1982). It is present in a number of neuroendocrine cells and its concentration in the CSF was reported to be 5.5 times that in plasma of healthy adults(Lofberg and Grubb, 1979; Lofberg et al., 1981; Lofberg et al., 1983). Grubb and Lofberg(1982) detected the protein in human pituitary gland, and suggested that it is part of the gastroenteropancreatic neuroendocrine system.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

No cross reactivity with other proteins

胱蛋白C

CST3

As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity.

胱蛋白C

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

tags & cell markers cell type markers tumor associated cell biology apoptosis intracellular caspases etc inhibitors stem cells neural stem cells extracellular cardiovascular atherosclerosis thrombosis

At -20ËšC for one year. After reconstitution, at 4ËšC for one month. It can also be aliquotted and stored frozen at -20ËšC for a longer time.Avoid repeated freezing and thawing.

Secreted .

Cystatin-C;Cystatin-3;Gamma-trace;Neuroendocrine basic polypeptide;Post-gamma-globulin;CST3;

Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in various body fluids, such as the cerebrospinal fluid and plasma. Expressed in highest levels in the epididymis, vas deferens, brain, thymus, and ovary and the lowest in the submandibular gland.

P01034