产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
抗体
产品名称 :
抗MEK3/MAP2K3抗体
目录 :
PA1377-1
规格 :
100μg/vial
价格 :
315美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹
图像
图像 1 :
武汉博士德生物工程有限公司 PA1377-1 图像 1
Anti-MEK3 antibody, PA1377-1, All Western blotting. All lanes: Anti-MAP2K3(PA1377-1) at 0.5ug/ml. Lane 1: Rat Skeletal Muscle Tissue Lysate at 40ug. Lane 2: Rat Kidney Tissue Lysate at 40ug. Lane 3: Rat Spleen Tissue Lysate at 40ug. Lane 4: HELA Whole Cell Lysate at 40ug. Lane 5: A549 Whole Cell Lysate at 40ug. Lane 6: JURKAT Whole Cell Lysate at 40ug. Lane 7: CEM Whole Cell Lysate at 40ug. Predicted bind size: 39KD. Observed bind size: 39KD
产品信息
SKU号 :
PA1377-1
产品名称 :
抗MEK3/MAP2K3抗体
价格 :
315美元
规格 :
100μg/vial
克隆性 :
多克隆
宿主 :
反应物种 :
人类, 小鼠, 大鼠
前体活性 :
仓鼠
应用(s) :
免疫印迹
应用细节 :
免疫印迹, 0.1 0.5µg/毫升, 人类, 大鼠, 小鼠
应用注释 :
Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
描述 :
Boster Bio Anti-MEK3/MAP2K3 Antibody catalog # PA1377-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
浓度 :
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
基因名称 :
MAP2K3
UniProt数据库编号 :
P46734
免疫原 :
A synthetic peptide corresponding to a sequence at the N-terminus of human MEK3 (42-58aa RNLDSRTFITIGDRNFE), identical to the related mouse and rat sequences.
形式 :
冻干
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
纯化 :
免疫原亲和纯化
交叉活性 :
No cross reactivity with other proteins
储存 :
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
重组 :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
基因全称 :
双特异性丝裂原活化蛋白激酶激酶3
同义词 :
双特异性丝裂原活化蛋白激酶激酶3;MKK 3;丝裂原活化蛋白激酶的激酶3;2.7。 12.2;MAPK/ERK激酶3;MEK 3;压力激活的蛋白激酶激酶2;SAPK激酶2;SAPKK-2;SAPKK2;MAP2K3;MEK3, MKK3, PRKMK3, SKK2;
蛋白名 :
双特异性丝裂原活化蛋白激酶激酶3(MKK 3/丝裂原活化蛋白激酶的激酶3)
分子量 :
39318分子量
Protein Function :
Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38.
组织特异性 :
Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.
Recommended Detection Systems :
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.
Sequence Similarities :
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
背景 :
Dual specificity mitogen-activated protein kinase kinase 3 is an enzyme that in humans is encoded by the MAP2K3 gene. The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. Rampoldi et al. (1997) localized the MAP2K3 gene to 17q11.2.
研究种类 :
酪氨酸激酶
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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