抗细胞色素P450 2d6抗体 | 武汉博士德生物工程有限公司 PA1397 产品信息

产品简要

公司名称 :

武汉博士德生物工程有限公司

产品类型 :

抗体

产品名称 :

抗细胞色素P450 2d6抗体

PA1397

规格 :

100 ug/vial

价格 :

200美元

克隆性 :

多克隆

宿主 :

兔

共轭标签 :

nonconjugated

反应物种 :

人类, 大鼠

应用 :

免疫印迹, 免疫组化-石蜡切片

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产品信息

SKU号 :

PA1397

名称 :

抗细胞色素P450 2d6抗体

价格 :

200美元

免疫原 :

A synthetic peptide corresponding to a sequence in the middle region of mouse Cytochrome P450 2D6(194-214aa FACRFEYNDPRFIRLLDLLKD), identical to the related rat sequence.

形式 :

冻干

宿主 :

兔

contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

纯化 :

免疫原亲和纯化

克隆性 :

多克隆

描述 :

Rabbit IgG polyclonal antibody for Cytochrome P450 2D6(CYP2D6) detection. Tested with WB, IHC-P in Mouse;Rat.

规格 :

100 ug/vial

反应物种 :

小鼠;大鼠

应用 :

免疫组化-P;免疫印迹

背景 :

Cytochrome P450 2D6(CYP2D6) is one of the most important enzymes involved in the metabolism of xenobiotics in the body. It is a member of Cytochrome P450, family 2, subfamily D, polypeptide 6. Its gene is mapped to chromosome 22q13.1. It has got 497 amino acid proteins which shares 73% sequence identity with the rat protein. CYP2D6 is highly expressed in human liver. CYP2D6 is the major isozyme involved in the formation of N-hydroxyprocainamide, a metabolite potentially involved in the drug-induced lupus syndrome observed with procainamide

浓度 :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

交叉活性 :

No cross reactivity with other proteins

基因全称 :

细胞色素P450 2d6

基因名称 :

CYP2D6

protein function :

Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants.

蛋白名 :

细胞色素P450 2d6

重组 :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

研究种类 :

cardiovascular lipids / lipoproteins lipid metabolism cytochromes signal transduction drug metabolism metabolism pathways and processes metabolic signaling pathways lipid and lipoprotein metabolism lipases mitochondrial metabolism

sequence similarities :

Belongs to the cytochrome P450 family.

储存 :

At -20ËšC for one year. After reconstitution, at 4ËšC for one month. It can also be aliquotted and stored frozen at -20ËšC for a longer time.Avoid repeated freezing and thawing.

subcellular localization :

Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

同义词 :

Cytochrome P450 2D6;1.14.14.1;CYPIID6;Cytochrome P450-DB1;Debrisoquine 4-hydroxylase;CYP2D6;CYP2DL1;

UniProt数据库编号 :

P10635

更多信息或购买 :

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