产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
抗体
产品名称 :
抗蛋白NDRG1 NDRG1抗体
目录 :
PA1416
规格 :
10微克样本
价格 :
99美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 免疫组化
图像
图像 1 :
武汉博士德生物工程有限公司 PA1416 图像 1
Anti-NDRG1 antibody, PA1416, Western blotting. Lane 1: SMMC Nucleus Cell Lysate. Lane 2: SMMC Cytoplasm Cell Lysate.
图像 2 :
武汉博士德生物工程有限公司 PA1416 图像 2
Anti-NDRG1 antibody, PA1416, IHC(P). IHC(P): Human Rectal Cancer Tissue
产品信息
SKU号 :
PA1416
状态 :
1
名称 :
抗蛋白NDRG1 NDRG1抗体
url key :
抗ndrg1抗体
产品种类 :
一抗
基因名称 :
NDRG1
价格 :
315
规格1 :
10微克样本
price for size 1 :
99美元
规格2 :
Full size
price for size 2 :
315
规格3 :
Full size carrier free
price for size 3 :
365
克隆性 :
多克隆
浓度 :
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
描述 :
Boster Bio Anti-Protein NDRG1 NDRG1 Antibody catalog # PA1416. Tested in IHC, WB applications. This antibody reacts with Human.
short description :
Boster Bio Anti-Protein NDRG1 NDRG1 Antibody catalog # PA1416. Tested in IHC, WB applications. This antibody reacts with Human.
规格 :
100μg/vial
UniProt数据库编号 :
Q92597
宿主 :
免疫原 :
A synthetic peptide corresponding to a sequence in the middle region of human NDRG1 (194-214aa HLFGKEEMQSNVEVVHTYRQH).
形式 :
冻干
纯化 :
免疫原亲和纯化
储存 :
Store at -20ÀöC for one year from date of receipt. After reconstitution, at 4ÀöC for one month. It can also be aliquotted and stored frozen at -20ÀöC for six months. Avoid repeated freeze-thaw cycles.
交叉活性 :
No cross reactivity with other proteins
重组 :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
应用细节 :
Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat. Western blot, 0.1-0.5ug/ml, Human.
应用 :
免疫组化, 免疫印迹
反应物种 :
人类
前体活性 :
狗, 马, 兔
images :
/antibody/pa1416-1-WB-anti-ndrg1-antibody.jpg /antibody/pa1416-2-IHC-anti-ndrg1-antibody.jpg
图像标记 :
Anti-NDRG1 antibody PA1416 Western blotting. Lane 1: SMMC Nucleus Cell Lysate. Lane 2: SMMC Cytoplasm Cell Lysate. Anti-NDRG1 antibody PA1416 IHC(P). IHC(P): Human Rectal Cancer Tissue
custom options :
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created at :
7/6/14 15:18
updated at :
3/2/22 2:54
meta title :
抗NDRG1/蛋白NDRG1抗体(PA1416)免疫组化验证
meta keyword :
抗蛋白NDRG1 NDRG1抗体
meta description :
Boster Bio Anti-Protein NDRG1 NDRG1 Antibody catalog # PA1416. Tested in IHC, WB applications. This antibody reacts with Human. Supplied as 100ug/vial in Lyophilized form antibody.
应用注释 :
Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
rating value :
95
背景 :
Protein NDRG1 is a protein that in humans is encoded by the NDRG1 gene. It is a member of the N-myc downregulated gene family which belong to the alpha/beta hydrolase superfamily. The NDRG1 gene is mapped to chromosome 8q24. It has got a deduced 394 amino acid protein with a molecular mass of 43kD. NDRG1 is expressed in the cytoplasm and basolateral membranes of gut lumen surface epithelial cells. The protein appears to play a vital role in growth arrest and cell differentiation.
competitor equivalent skus :
sc 19464 sc 19466 sc 100786 sc 30040 sc 398291 sc 398823
研究种类 :
Angiogenesis,Cancer,Cancer Susceptibility,Epigenetics And Nuclear Signaling,Invasion/Microenvironment,Neural Signal Transduction,Neurodegenerative Disease,Neurology Process,Neuroscience,Oncoproteins,Oncoproteins/Suppressors,Proto-Oncogenes,Transcription
同义词 :
Protein NDRG1;Differentiation-related gene 1 protein;DRG-1;N-myc downstream-regulated gene 1 protein;Nickel-specific induction protein Cap43;Reducing agents and tunicamycin-responsive protein;RTP;Rit42;NDRG1;CAP43, DRG1, RTP;
基因全称 :
蛋白NDRG1
分子量 :
42835分子量
protein function :
Stress-responsive protein involved in hormone responses, cell growth, and differentiation. Acts as a tumor suppressor in many cell types. Necessary but not sufficient for p53/TP53- mediated caspase activation and apoptosis. Has a role in cell trafficking, notably of the Schwann cell, and is necessary for the maintenance and development of the peripheral nerve myelin sheath. Required for vesicular recycling of CDH1 and TF. May also function in lipid trafficking. Protects cells from spindle disruption damage. Functions in p53/TP53-dependent mitotic spindle checkpoint. Regulates microtubule dynamics and maintains euploidy.
subcellular localization :
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cell membrane. Mainly cytoplasmic but differentially localized to other regions. Associates with the plasma membrane in intestinal epithelia and lactating mammary gland. Translocated to the nucleus in a p53/TP53-dependent manner. In prostate epithelium and placental chorion, located in both the cytoplasm and in the nucleus. No nuclear localization in colon epithelium cells. In intestinal mucosa, prostate and renal cortex, located predominantly adjacent to adherens junctions. Cytoplasmic with granular staining in proximal tubular cells of the kidney and salivary gland ducts. Recruits to the membrane of recycling/sorting and late endosomes via binding to phosphatidylinositol 4-phosphate. Associates with microtubules. Colocalizes with TUBG1 in the centrosome. Cytoplasmic location increased with hypoxia. Phosphorylated form found associated with centromeres during S-phase of mitosis and with the plasma membrane.
组织特异性 :
Ubiquitous; expressed most prominently in placental membranes and prostate, kidney, small intestine, and ovary tissues. Also expressed in heart, brain, skeletal muscle, lung, liver and pancreas. Low levels in peripheral blood leukocytes and in tissues of the immune system. Expressed mainly in epithelial cells. Also found in Schwann cells of peripheral neurons. Reduced expression in adenocarcinomas compared to normal tissues. In colon, prostate and placental membranes, the cells that border the lumen show the highest expression.
蛋白名 :
蛋白NDRG1
recommended detection systems :
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
sequence similarities :
Belongs to the NDRG family.
template :
抗体
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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