产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
抗体
产品名称 :
抗GPR2/CCR10抗体
目录 :
PA1491
规格 :
10微克样本
价格 :
99美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹
图像
图像 1 :
武汉博士德生物工程有限公司 PA1491 图像 1
Anti-GPR2/CCR10 antibody, PA1491, Western blotting. Lane 1: HELA Cell Lysate. Lane 2: SW620 Cell Lysate. Lane 3: A549 Cell Lysate. Lane 4: MM231 Cell Lysate. Lane 5: SMMC Cell Lysate.
产品信息
SKU号 :
PA1491
状态 :
1
名称 :
抗GPR2/CCR10抗体
url key :
抗gpr2-ccr10
产品种类 :
一抗
基因名称 :
CCR10
价格 :
315
规格1 :
10微克样本
price for size 1 :
99美元
规格2 :
Full size
price for size 2 :
315
规格3 :
Full size carrier free
price for size 3 :
365
克隆性 :
多克隆
浓度 :
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
描述 :
Boster Bio Anti-GPR2/CCR10 Antibody catalog # PA1491. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
short description :
Boster Bio Anti-GPR2/CCR10 Antibody catalog # PA1491. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
规格 :
100μg/vial
UniProt数据库编号 :
P46092
宿主 :
免疫原 :
A synthetic peptide corresponding to a sequence at the C-terminus of human GPR2/CCR10 (312-327aa FLGLRFRQDLRRLLRG), different from the related rat and mouse sequences by one amino acid.
形式 :
冻干
纯化 :
免疫原亲和纯化
储存 :
Store at -20ÀöC for one year from date of receipt. After reconstitution, at 4ÀöC for one month. It can also be aliquotted and stored frozen at -20ÀöC for six months. Avoid repeated freeze-thaw cycles.
交叉活性 :
No cross reactivity with other proteins
重组 :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
应用细节 :
免疫印迹, 0.1 0.5微克/毫升, 人类, 大鼠, 小鼠
应用 :
免疫印迹
反应物种 :
大鼠, 小鼠, 人类
前体活性 :
仓鼠
images :
/antibody/pa1491-1-WB-anti-gpr2-ccr10-antibody.jpg
图像标记 :
Anti-GPR2/CCR10 antibody PA1491 Western blotting. Lane 1: HELA Cell Lysate. Lane 2: SW620 Cell Lysate. Lane 3: A549 Cell Lysate. Lane 4: MM231 Cell Lysate. Lane 5: SMMC Cell Lysate.
custom options :
name=Size,required=1,price=-216.0000,type=radio,sku=,max_characters=0,file_extension=,image_size_x=0,image_size_y=0,price_type=fixed,option_title=10ug sample name=Size,required=1,price=0.0000,type=radio,sku=,max_characters=0,file_extension=,image_size_x=0,image_size_y=0,price_type=fixed,option_title=Full size name=Size,required=1,price=50.0000,type=radio,sku=,max_characters=0,file_extension=,image_size_x=0,image_size_y=0,price_type=fixed,option_title=Full size carrier free
created at :
7/6/14 15:18
updated at :
3/2/22 2:54
meta title :
抗GPR2/CCR10抗体
meta keyword :
抗GPR2/CCR10抗体
meta description :
Boster Bio Anti-GPR2/CCR10 Antibody catalog # PA1491. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. Supplied as 100ug/vial in Lyophilized form antibody.
应用注释 :
Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
rating value :
97.6
背景 :
CCR10, C-C chemokine receptor type 10 is a protein that in humans is encoded by the CCR10 gene. CCR10 is constitutively expressed in skin melanocytes, fibroblasts, and microvascular endothelial cells, and that it is upregulated by IL1B and TNF. Expression was also detected in T cells, Langerhans cells, and peripheral blood mononuclear cells but not in dendritic cells.By fluorescence in situ hybridization, the GPR2 gene is mapped to 17q21.1-q21.3. CCR10 is the receptor for CCL27. CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation. expression of CCL27 in normal keratinocytes and its strong upregulation in skin lesions of atopic dermatitis, contact dermatitis, and psoriasis patients. CCR10+ T lymphocytes were detected in lesional but not normal skin of these patients. Flow cytometric analysis showed that CCL27 binds extracellular matrix components and dermal microvascular endothelial cells and fibroblasts and mediates adhesion and transendothelial migration of CCR10+ circulating leukocytes. CCR10 is predominantly expressed on CD4+CLA+ (cutaneous lymphocyte antigen), rather than CD8+, circulating T cells. RT-PCR, confocal microscopy, and ELISA analysis indicated that keratinocytes exposed to TNF or IL1B but not to IL4 or IFNG in vitro express increased CCL27.
competitor equivalent skus :
sc 134980 sc 16995 sc 30035 sc 365531 sc 365718 sc 365957 sc 46835 sc 46836 sc 67468
研究种类 :
Chemokines,Immunology,Innate Immunity
同义词 :
C-趋化因子C受体类型10;C-C CKR-10;CC-CKR;CCR-10;G蛋白偶联受体2;CCR10;GPR2;
基因全称 :
C-趋化因子C受体类型10
分子量 :
38416分子量
protein function :
Receptor for chemokines SCYA27 and SCYA28. Subsequently transduces a signal by increasing the intracellular calcium ions level and stimulates chemotaxis in a pre-B cell line.
subcellular localization :
Cell membrane; Multi-pass membrane protein.
组织特异性 :
Expressed at high levels in adult testis, small intestine, fetal lung, fetal kidney. Weaker expression was observed in many other adult tissues including spleen, thymus, lymph node, Peyer patches, colon, heart, ovary, peripheral blood lymphocytes, thyroid and spinal cord. Also expressed by melanocytes, dermal fibroblasts, dermal microvascular endothelial cells. Also detected in T-cells and in skin-derived Langerhans cells.
蛋白名 :
C-趋化因子C受体类型10(C-C CKR-10/CC-CKR-10/CCR-10)
recommended detection systems :
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.
sequence similarities :
Belongs to the G-protein coupled receptor 1 family.
template :
抗体
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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