抗体

抗核纤层蛋白B2/LMNB2抗体

PA1636

100μg/vial

315美元

多克隆

domestic rabbit

未共轭

人类, 小鼠, 大鼠

免疫印迹, 免疫组化-石蜡切片, 免疫组化-冰冻切片

抗核纤层蛋白B2/LMNB2抗体

315美元

100μg/vial

多克隆

兔

人类, 小鼠, 大鼠

仓鼠

免疫组化-P, 免疫组化-F, 免疫印迹

Immunohistochemistry (Frozen Section), 0.5-1µg/ml, Rat, Human, MouseImmunohistochemistry (Paraffin-embedded Section), 0.5-1µg/ml, Human, Rat, Mouse, By Heat. Western blot, 0.1-0.5µg/ml, Human, Mouse, Rat.

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Boster Bio Anti-Lamin B2/LMNB2 Antibody catalog # PA1636. Tested in IHC-P, IHC-F, WB applications. This antibody reacts with Human, Mouse, Rat.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

LMNB2

Q03252

A synthetic peptide corresponding to a sequence at the C-terminus of human Lamin B2 (580-597aa EEDLFHQQGDPRTTSRGC), identical to the related rat and mouse sequences.

冻干

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

免疫原亲和纯化

No cross reactivity with other proteins

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

核纤层蛋白B2

核纤层蛋白B2;LMNB2;LMN2;

核纤层蛋白B2

67689分子量

Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.

Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side.

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P) and IHC(F).

Belongs to the intermediate filament family.

Lamin B2, also called LMNB2, is a protein associated with laminopathies. The LMNB2 gene is mapped to the G-negative subtelomeric band p13.3 of chromosome 19 by in situ hybridization. The LMNB2 gene contains 12 exons. Model organisms have been used in the study of Lamin B2 function. A conditional knockout mouse line, called Lmnb2, is generated as part of the International Knockout Mouse Consortium program-a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists. A highly sensitive procedure about mapping the start site of DNA replication in a 13.7-kb region of human chromosome 19 coding for lamin B2 is developed for the identification of the origin of bidirectional DNA synthesis in single-copy replicons of mammalian cells.

Apoptosis, Cancer, Cell Biology, Cell Death, Chromosome Structure, Cytoskeleton, Cytoskeleton / Ecm, Epigenetics and Nuclear Signaling, Intermediate Filaments, Nucleus, Signal Transduction, Subcellular Markers, Tags & Cell Markers