产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
抗体
产品名称 :
抗IL2RA抗体
目录 :
PA1747
规格 :
100μg/vial
价格 :
315美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 免疫组化
图像
图像 1 :
武汉博士德生物工程有限公司 PA1747 图像 1
Anti- CD25/IL-2sR Alpha antibody, PA1747, Western blotting. All lanes: Anti CD25/IL-2sR Alpha (PA1747) at 0.5ug/ml. Lane 1: SMMC Whole Cell Lysate at 40ug. Lane 2: A549 Whole Cell Lysate at 40ug. Lane 3: JURKAT Whole Cell Lysate at 40ug. Lane 4: MCF-7 Whole Cell Lysate at 40ug. Lane 5: RAJI Whole Cell Lysate at 40ug. Lane 6: PANC Whole Cell Lysate at 40ug. Predicted bind size: 31KD. Observed bind size: 45KD
图像 2 :
武汉博士德生物工程有限公司 PA1747 图像 2
Anti- CD25/IL-2sR Alpha antibody, PA1747, IHC(P). IHC(P): Human Tonsil Tissue
产品信息
SKU号 :
PA1747
产品名称 :
抗IL2RA抗体
价格 :
315美元
规格 :
100μg/vial
克隆性 :
多克隆
宿主 :
反应物种 :
人类
应用(s) :
免疫组化, 免疫印迹
应用细节 :
Immunohistochemistry (Paraffin-embedded Section), 0.5-1µg/ml, Human, By Heat. Western blot, 0.1-0.5µg/ml, Human.
应用注释 :
Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
描述 :
Boster Bio Anti-IL2RA Antibody catalog # PA1747. Tested in IHC, WB applications. This antibody reacts with Human.
浓度 :
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
基因名称 :
IL2RA
UniProt数据库编号 :
P01589
免疫原 :
A synthetic peptide corresponding to a sequence at the N-terminus of human CD25/IL-2sR Alpha (39-57aa MAYKEGTMLNCECKRGFRR).
形式 :
冻干
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
纯化 :
免疫原亲和纯化
交叉活性 :
No cross reactivity with other proteins
储存 :
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
重组 :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
基因全称 :
白细胞介素2受体亚单位甲
同义词 :
白细胞介素2受体亚单位甲;IL-2受体亚单位甲;IL-2;IL-2R亚单位甲;白细胞介素-RA;TAC抗原;p55;CD25;IL2RA;
蛋白名 :
白细胞介素2受体亚单位甲(IL-2受体亚单位甲/IL-2/IL-2R亚单位甲/白细胞介素-RA)
分子量 :
30819分子量
Protein Function :
Receptor for interleukin-2.
Subcellular Localization :
Membrane; Single-pass type I membrane protein.
Recommended Detection Systems :
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
Sequence Similarities :
Contains 2 Sushi (CCP/SCR) domains.
背景 :
IL2RA (Interleukin 2 receptor, alpha), also called IL2R, IL2R, Alpha Chain or CD25, is a protein that in humans is encoded by the IL2RA gene.The IL2RA gene is mapped on 10p15.1. IL2RA is composed of strand-swapped "sushi-like" domains, unlike the classical cytokine receptor fold. As a result of this domain swap, IL2RA uses a composite surface to dock into a groove on IL2 that also serves as a binding site for antagonist drugs.Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Infection by the protozoan Trypanosoma cruzi causes Chagas disease, characterized by a reduction in the amount of IL2RA expressed on the surface of immune cells. This leads to chronic immune suppression, becoming increasingly severe over the course of many years and ultimately resulting in death if left untreated.
研究种类 :
Adaptive Immunity, Cytokines, Immunology, Innate Immunity, Interleukins, T Cells
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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