产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
抗体
产品名称 :
抗细胞色素P450还原酶/POR抗体
目录 :
PA1952
规格 :
100μg/vial
价格 :
315美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
图像
图像 1 :
武汉博士德生物工程有限公司 PA1952 图像 1
Anti-POR antibody, PA1952, Western blotting. Lane 1: Rat Ovary Tissue Lysate. Lane 2: Rat Lung Tissue Lysate. Lane 3: Rat Testis Tissue Lysate. Lane 4: Rat Spleen Tissue Lysate. Lane 5: A549 Cell Lysate . Lane 6: HELA Cell Lysate. Lane 7: SKOV Cell Lysate. Lane 8: MCF-7 Cell Lysate
图像 2 :
武汉博士德生物工程有限公司 PA1952 图像 2
Anti-POR antibody, PA1952, IHC(P). IHC(P): Human Placenta Tissue
图像 3 :
武汉博士德生物工程有限公司 PA1952 图像 3
Anti-POR antibody, PA1952, ICC. ICC: HELA Cell
产品信息
SKU号 :
PA1952
产品名称 :
抗细胞色素P450还原酶/POR抗体
价格 :
315美元
规格 :
100μg/vial
克隆性 :
多克隆
宿主 :
反应物种 :
人类, 小鼠, 大鼠
前体活性 :
仓鼠
应用(s) :
流式细胞仪, 免疫组化-P, 免疫细胞化学, 免疫印迹
应用细节 :
Immunohistochemistry (Paraffin-embedded Section), 0.5-1µg/ml, Human, Mouse, Rat, By Heat. Immunocytochemistry, 0.5-1µg/ml, Human Western blot, 0.1-0.5µg/ml, Human, Mouse, Rat.Flow Cytometry, 1-3μg/1x10^6 cells, Human.
应用注释 :
Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
描述 :
Boster Bio Anti-Cytochrome P450 Reductase/POR Antibody catalog # PA1952. Tested in Flow Cytometry, IHC-P, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
浓度 :
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
基因名称 :
POR
UniProt数据库编号 :
P16435
免疫原 :
A synthetic peptide corresponding to a sequence at the C-terminus of human POR (659-677aa DYIKKLMTKGRYSLDVWS), different from the related rat and mouse sequences by one amino acid.
形式 :
冻干
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
纯化 :
免疫原亲和纯化
交叉活性 :
No cross reactivity with other proteins
储存 :
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
重组 :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
基因全称 :
NADPH细胞色素P还原酶
同义词 :
NADPH细胞色素P还原酶;CPR;P450R;1.6。 2.4;POR;CYPOR;
蛋白名 :
NADPH细胞色素P还原酶
分子量 :
76690分子量
Protein Function :
This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5.
Subcellular Localization :
Endoplasmic reticulum membrane; Peripheral membrane protein. Anchored to the ER membrane by its N- terminal hydrophobic region.
Recommended Detection Systems :
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P) and ICC.
Sequence Similarities :
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
背景 :
POR is a membrane-boundenzyme required for electron transfer from NADPH to cytochrome P450 in the endoplasmic reticulum of theeukaryotic cell. The gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.
研究种类 :
Cancer, Metabolism, Mitochondria, Mitochondrial, Mitochondrial Markers, Mitochondrial Metabolism, Organelles, Pathways And Processes, Signal Transduction, Subcellular Markers
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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