抗体

抗E钙粘蛋白/CDH1抗体

PA2078

100 ug/vial

240美元

多克隆

兔

nonconjugated

Enabled

抗E钙粘蛋白/CDH1抗体

一抗, 多克隆抗体

CDH1

240美元

30ug sample size / $99 100ug / $240 100ug+Free HRP Secondary BA1054 / $240 100ug+Free Biotin Secondary BA1003 / $240

多克隆

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

No

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Polyclonal antibody for E CADHERIN/CDH1 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: WB. Reactive species: Human. E CADHERIN/CDH1 information: Molecular Weight: 97456 MW; Subcellular Localization: Cell junction. Cell membrane; Single-pass type I membrane protein. Endosome. Golgi apparatus, trans-Golgi network. Colocalizes with DLGAP5 at sites of cell-cell contact in intestinal epithelial cells. Anchored to actin microfilaments through association with alpha-, beta- and gamma- catenin. Sequential proteolysis induced by apoptosis or calcium influx, results in translocation from sites of cell-cell contact to the cytoplasm. Colocalizes with RAB11A endosomes during its transport from the Golgi apparatus to the plasma membrane; Tissue Specificity: Non-neural epithelial tissues.

Rabbit IgG polyclonal antibody for Cadherin-1(CDH1) detection. Tested with WB in Human.

100 ug/vial

30ug for $99, contact us for details

P12830

兔

A synthetic peptide corresponding to a sequence at the C-terminus of human E Cadherin(662-677aa DYKINLKLMDNQNKDQ).

冻干

免疫原亲和纯化

At -20 C for one year. After reconstitution, at 4 C for one month. It can also be aliquotted and stored frozen at -20 C for a longer time.Avoid repeated freezing and thawing.

No cross reactivity with other proteins

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

免疫印迹, 0.1 0.5微克/毫升, 人类

免疫印迹

人类

仓鼠

Anti-E Cadherin antibody, PA2078, Western blotting. Lane 1: A549 Cell Lysate. Lane 2: SGC Cell Lysate.

CDH1(Cadherin 1), also known as ECAD or UVO, is a protein that in humans is encoded by the CDH1 gene. Cadherin-1 is a classical member of the cadherin superfamily. By Southern analysis of DNA from a panel of mouse-human somatic cell hybrids, Mansouri et al.(1987, 1988) assigned the UVO gene to 16q(16p11-qter). Frebourg et al.(2006) found that in human embryos CDH1 is highly expressed at 4 and 5 weeks in the frontonasal prominence and at 6 weeks in the lateral and medial nasal prominences, and is therefore expressed during critical stages of lip and palate development. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.

sc 25250 sc 69784 sc 366443

Cadherins, Calcium Binding Proteins, Calcium Signaling, Cancer, Cell Adhesion, Cytoskeleton / Ecm, Invasion/Microenvironment, Signal Transduction, Signaling Pathway

Cadherin-1;CAM 120/80;Epithelial cadherin;E-cadherin;Uvomorulin;CD324;E-Cad/CTF1;E-Cad/CTF2;E-Cad/CTF3;CDH1;CDHE, UVO;

钙粘蛋白1

97456分子量

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.

Cell junction. Cell membrane; Single-pass type I membrane protein. Endosome. Golgi apparatus, trans-Golgi network. Colocalizes with DLGAP5 at sites of cell-cell contact in intestinal epithelial cells. Anchored to actin microfilaments through association with alpha-, beta- and gamma- catenin. Sequential proteolysis induced by apoptosis or calcium influx, results in translocation from sites of cell-cell contact to the cytoplasm. Colocalizes with RAB11A endosomes during its transport from the Golgi apparatus to the plasma membrane.

Non-neural epithelial tissues.

钙粘蛋白1

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.

含5钙粘蛋白区域

1/28/19 19:39