产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
抗体
产品名称 :
抗HYAL1抗体
目录 :
PA2181-1
规格 :
100 ug/vial
价格 :
280美元
克隆性 :
多克隆
宿主 :
共轭标签 :
nonconjugated
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫细胞化学
图像
图像 1 :
武汉博士德生物工程有限公司 PA2181-1 图像 1
Anti-HYAL1 antibody, PA2181-1, IHC(P). IHC(P): Human Intestinal Cancer Tissue
图像 2 :
武汉博士德生物工程有限公司 PA2181-1 图像 2
Anti-HYAL1 antibody, PA2181-1, ICC. ICC: MCF-7 Cell
图像 3 :
武汉博士德生物工程有限公司 PA2181-1 图像 3
Anti-HYAL1 antibody, PA2181-1, Western blotting. Lane 1: HELA Cell Lysate. Lane 2: 22RV1 Cell Lysate. Lane 3: MCF-7 Cell Lysate.
产品信息
SKU号 :
PA2181-1
状态 :
Enabled
名称 :
抗HYAL1抗体
目录名称 :
一抗, 多克隆抗体, 免疫组化免疫细胞化学IF抗体
基因名称 :
HYAL1
价格 :
280美元
price various sizes :
30ug sample size / $99 100ug / $280 100ug+Free HRP Secondary BA1054 / $280 100ug+Free Biotin Secondary BA1003 / $280
克隆性 :
多克隆
浓度 :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
共轭标签 :
No
contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
描述 :
Polyclonal antibody for HYAL1 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: IHC-P. Reactive species: Human. HYAL1 information: Molecular Weight: 48368 MW; Subcellular Localization: Secreted . Lysosome ; Tissue Specificity: Highly expressed in the liver, kidney and heart. Weakly expressed in lung, placenta and skeletal muscle. No expression detected in adult brain. Isoform 1 is expressed only in bladder and prostate cancer cells, G2/G3 bladder tumor tissues and lymph node specimens showing tumor invasive tumors cells. Isoform 3, isoform 4, isoform 5 and isoform 6 are expressed in normal bladder and bladder tumor tissues.
short description :
Rabbit IgG polyclonal antibody for Hyaluronidase-1(HYAL1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human.
规格 :
100 ug/vial
sample size available :
30ug for $99, contact us for details
UniProt数据库编号 :
Q12794
宿主 :
免疫原 :
A synthetic peptide corresponding to a sequence at the N-terminus of human HYAL1(32-47aa FTTVWNANTQWCLERH).
形式 :
冻干
纯化 :
免疫原亲和纯化
储存 :
At -20 C for one year. After reconstitution, at 4 C for one month. It can also be aliquotted and stored frozen at -20 C for a longer time.Avoid repeated freezing and thawing.
交叉活性 :
No cross reactivity with other proteins
重组 :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
应用细节 :
Immunocytochemistry , 0.5-1ug/ml, Human, -. Immunohistochemistry(Frozen Section), 0.5-1ug/ml, Human, -. Immunohistochemistry(Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat. Western blot, 0.1-0.5ug/ml, Human.
应用 :
免疫组化, 免疫细胞化学, 免疫印迹
反应物种 :
人类
图像标记 :
Anti-HYAL1 antibody, PA2181-1, IHC(P). IHC(P): Human Intestinal Cancer Tissue Anti-HYAL1 antibody, PA2181-1, ICC. ICC: MCF-7 Cell Anti-HYAL1 antibody, PA2181-1, Western blotting. Lane 1: HELA Cell Lysate. Lane 2: 22RV1 Cell Lysate. Lane 3: MCF-7 Cell Lysate. Anti-HYAL1 antibody, PA2181-1, IHC(F). IHC(F): Human Placenta Tissue
背景 :
Hyaluronidase-1, also known as HYAL1 or LUCA1, is an enzyme that in humans is encoded by the HYAL1 gene. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is though to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency.
competitor equivalent skus :
sc 99448 sc 101341 sc 101340 sc 366417 sc 366416 sc 514634
研究种类 :
Cancer, Cytoskeleton / Ecm, Ecm Enzymes, Ecm Proteins, Extracellular Matrix, Invasion/Microenvironment, Signal Transduction
同义词 :
Hyaluronidase-1;Hyal-1;3.2.1.35;Hyaluronoglucosaminidase-1;Lung carcinoma protein 1;LuCa-1;HYAL1;LUCA1;
基因全称 :
透明质酸酶1
分子量 :
48368分子量
protein function :
May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth.
subcellular localization :
Secreted . Lysosome .
组织特异性 :
Highly expressed in the liver, kidney and heart. Weakly expressed in lung, placenta and skeletal muscle. No expression detected in adult brain. Isoform 1 is expressed only in bladder and prostate cancer cells, G2/G3 bladder tumor tissues and lymph node specimens showing tumor invasive tumors cells. Isoform 3, isoform 4, isoform 5 and isoform 6 are expressed in normal bladder and bladder tumor tissues.
蛋白名 :
透明质酸酶1
recommended detection systems :
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P), IHC(F) and ICC.
sequence similarities :
Belongs to the glycosyl hydrolase 56 family.
更新 :
1/28/19 19:39
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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