产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
抗体
产品名称 :
Anti-SYBL1/VAMP7 Antibody Picoband™
目录 :
PB10017
规格 :
100μg/vial
价格 :
315美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 大鼠
应用 :
免疫印迹
图像
图像 1 :
武汉博士德生物工程有限公司 PB10017 图像 1
Western blot analysis of SYBL1 expression in rat liver extract (lane 1) and HELA whole cell lysates (lane 3). SYBL1 at 25KD was detected using rabbit anti- SYBL1 Antigen Affinity purified polyclonal antibody (Catalog # PB10017) at 0.5 ??g/mL. The blot was developed using chemiluminescence (ECL) method (Catalog # EK1002).
产品信息
SKU号 :
PB10017
产品名称 :
Anti-SYBL1/VAMP7 Antibody Picoband™
价格 :
315美元
规格 :
100μg/vial
克隆性 :
多克隆
宿主 :
反应物种 :
人类, 大鼠
前体活性 :
Bovine, Horse, Monkey, Rabbit
应用(s) :
免疫印迹
应用细节 :
免疫印迹, 0.1 0.5µg/毫升, 人类, 大鼠
应用注释 :
Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
描述 :
Boster Bio Anti-SYBL1/VAMP7 Antibody Picoband™ catalog # PB10017. Tested in WB applications. This antibody reacts with Human, Rat.
浓度 :
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
基因名称 :
VAMP7
UniProt数据库编号 :
P51809
免疫原 :
E. coli-derived human SYBL1 recombinant protein (Position: N24-T190). Human SYBL1 shares 97.6% and 95.2% amino acid (aa) sequence identity with mouse and rat SYBL1, respectively.
形式 :
冻干
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
纯化 :
免疫原亲和纯化
交叉活性 :
No cross reactivity with other proteins
储存 :
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
重组 :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
基因全称 :
Vesicle-associated membrane protein 7
同义词 :
Vesicle-associated membrane protein 7; VAMP-7; Synaptobrevin-like protein 1; Tetanus-insensitive VAMP; Ti-VAMP; VAMP7; SYBL1;
蛋白名 :
Vesicle-associated membrane protein 7
分子量 :
24935分子量
Protein Function :
Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Required for focal exocytosis of late endocytic vesicles during phagosome formation.
Subcellular Localization :
Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass type IV membrane protein. Golgi apparatus, trans-Golgi network membrane ; Single-pass type IV membrane protein. Late endosome membrane ; Single-pass type IV membrane protein. Lysosome membrane ; Single-pass type IV membrane protein. Endoplasmic reticulum membrane ; Single-pass type IV membrane protein. Cytoplasmic vesicle, phagosome membrane ; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome. In immature neurons expression is localized in vesicular structures in axons and dendrites while in mature neurons it is localized to the somatodendritic region. Colocalizes with LAMP1 in kidney cells. Localization to the endoplasmic reticulum membrane was observed in the intestine but not in liver or kidney (By similarity).
组织特异性 :
Detected in all tissues tested.
Recommended Detection Systems :
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.
背景 :
Vesicle-associated membrane protein 7 (VAMP-7), also known as SYBL1, is a protein that in humans is encoded by the VAMP7 gene. This gene encodes a transmembrane protein that is a member of the soluble N-ethylmaleimide- sensitive factor attachment protein receptor (SNARE) family. The encoded protein localizes to late endosomes and lysosomes and is involved in the fusion of transport vesicles to their target membranes. Alternate splicing results in multiple transcript variants.
研究种类 :
Protein Trafficking, Signal Transduction, Vesicle Transport
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
Premium Provider of Antibodies and ELISA Kits