抗体

Anti-alpha 1 Antitrypsin/SERPINA1 Antibody Picoband™

PB10097

100μg/vial

315美元

多克隆

domestic rabbit

未共轭

人类, 大鼠

Anti-alpha 1 Antitrypsin/SERPINA1 Antibody Picoband™

315美元

100μg/vial

多克隆

兔

人类, 大鼠

免疫印迹

免疫印迹, 0.1 0.5µg/毫升, 人类, 大鼠

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Boster Bio Anti-alpha 1 Antitrypsin/SERPINA1 Antibody Picoband™ catalog # PB10097. Tested in WB applications. This antibody reacts with Human, Rat.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

SERPINA1

P01009

E. coli-derived human SERPINA1 recombinant protein (Position: E25-T204). Human SERPINA1 shares 72.8% amino acid (aa) sequence identity with rat SERPINA1.

冻干

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

免疫原亲和纯化

No cross reactivity with other proteins.

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

甲1

Alpha-1-antitrypsin; Alpha-1 protease inhibitor; Alpha-1-antiproteinase; Serpin A1; Short peptide from AAT; SPAAT; SERPINA1; AAT, PI; PRO0684, PRO2209;

甲1

46737分子量

Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.

Secreted. Endoplasmic reticulum. The S and Z allele are not secreted effectively and accumulate intracellularly in the endoplasmic reticulum.

Ubiquitous. Expressed in leukocytes and plasma.

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.

SERPINA1 is also known as PI, A1A or AAT. This gene is mapped to 14q32.1. The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene.

Apoptosis, Cancer, Cancer Metabolism, Cardiovascular, Cell Biology, Intracellular, Kinases, Metabolism, Metabolism Processes, Pathways And Processes, Protease Inhibitors, Proteolysis / Ubiquitin, Response To Hypoxia, Serum Proteins